Sonja N. Brun, Ph.D.
Affiliations: | 2014 | Pharmacology | Duke University, Durham, NC |
Area:
Oncology, Pharmacology, Molecular BiologyGoogle:
"Sonja Brun"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Donald P. McDonnell | grad student | 2014 | Duke | |
| (Molecular Regulators of Stem Cell Fate and Tumor Development in the Cerebellum.) | ||||
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Publications
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| Montgomery MK, Duan C, Manzuk L, et al. (2023) Applying deep learning to segmentation of murine lung tumors in pre-clinical micro-computed tomography. Translational Oncology. 40: 101833 |
| Eichner LJ, Curtis SD, Brun SN, et al. (2023) HDAC3 is critical in tumor development and therapeutic resistance in -mutant non-small cell lung cancer. Science Advances. 9: eadd3243 |
| Lin C, Blessing AM, Pulliam TL, et al. (2021) Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling. Oncogene |
| Hollstein PE, Eichner LJ, Brun SN, et al. (2019) The AMPK-related kinases SIK1 and SIK3 mediate key tumor suppressive effects of LKB1 in NSCLC. Cancer Discovery |
| Limpert AS, Lambert LJ, Bakas NA, et al. (2018) Autophagy in Cancer: Regulation by Small Molecules. Trends in Pharmacological Sciences. 39: 1021-1032 |
| Eichner LJ, Brun SN, Herzig S, et al. (2018) Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models. Cell Metabolism |
| Svensson RU, Parker SJ, Eichner LJ, et al. (2016) Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models. Nature Medicine |
| Brun SN, Markant SL, Esparza LA, et al. (2015) Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma. Oncogene. 34: 3770-9 |
| Emmenegger BA, Hwang EI, Moore C, et al. (2013) Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma. Oncogene. 32: 4181-8 |
| Pei Y, Brun SN, Markant SL, et al. (2012) WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development (Cambridge, England). 139: 1724-33 |