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Susan E. Leeman, PhD

Affiliations: 
Pharmacology Boston University School of Medicine, Boston, MA 
Area:
Neuroscience
Website:
http://www.bumc.bu.edu/busm-pm/faculty/faculty-profiles/leeman/
Google:
"Susan Leeman"
Bio:

http://www.sfn.org/~/media/SfN/Documents/TheHistoryofNeuroscience/Volume%206/c9.ashx
Member National Academy of Sciences. Discovered neuroactive actions for substance-P and neurotensin.

Mean distance: 15.05 (cluster 32)
 		SNBCP
Cross-listing: Chemistry Tree

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Parents

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Paul L. Munson grad student 1954 Radcliffe College
 (The problem of neurohormonal stimulation of the secretion of adrenocorticotropic hormone)

Children

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Douglas Macdonald grad student CHDI Management
Caroline E. Fisher grad student 2000 Boston University
Lori J. Fitz grad student 2006 Boston University
Morris F. Tansky grad student 2006 Boston University
Karen M. Bourque grad student 2007 Boston University
Kristen N. Bushell grad student 2010 Boston University
Patricia W. Bedard grad student 2011 Boston University
Rebecca M. Burke grad student 2012 Boston University
Earl Gillespie grad student 2013 Boston University
David H. Farb post-doc Boston University

Collaborators

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Publications

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Douglas SD, Leeman SE. (2018) Is substance P a nasal epithelial neuropeptide? The Journal of Allergy and Clinical Immunology
Taracanova A, Alevizos M, Karagkouni A, et al. (2017) SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. Proceedings of the National Academy of Sciences of the United States of America
Patel AB, Tsilioni I, Leeman SE, et al. (2016) Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism. Proceedings of the National Academy of Sciences of the United States of America
Yuan H, Zelkha S, Zelka S, et al. (2013) Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E5059-68
Burke RM, Norman TA, Haydar TF, et al. (2013) BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 19567-72
Bhargava A, Clifton MS, Mhaske P, et al. (2013) Local injection of dsRNA targeting calcitonin receptor-like receptor (CLR) ameliorates Clostridium difficile toxin A-induced ileitis. Proceedings of the National Academy of Sciences of the United States of America. 110: 731-6
Gillespie E, Leeman SE, Watts LA, et al. (2013) Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. Journal of Crohn's & Colitis. 7: 403-11
Bushell KN, Leeman SE, Gillespie E, et al. (2011) LITAF mediation of increased TNF-α secretion from inflamed colonic lamina propria macrophages. Plos One. 6: e25849
Gillespie E, Leeman SE, Watts LA, et al. (2011) Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 17420-5
Meshki J, Douglas SD, Hu M, et al. (2011) Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. Plos One. 6: e25332
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