Jeffrey J. Kovacs, Ph.D.

Affiliations: 
2005 Duke University, Durham, NC 
Area:
Molecular Biology, Pharmacology
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"Jeffrey Kovacs"
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Parents

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Tso-Pang Yao grad student 2005 Duke
 (Characterization of novel domains and functions of HDAC6, a multifaceted deacetylase.)
Robert J. Lefkowitz post-doc Duke
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Publications

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Ma Z, Yu YR, Badea CT, et al. (2018) Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1. Circulation
Kotula JW, Sun J, Li M, et al. (2014) Targeted disruption of β-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth. Plos One. 9: e93441
Simard E, Kovacs JJ, Miller WE, et al. (2013) β-Arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration. Plos One. 8: e80532
Fereshteh M, Ito T, Kovacs JJ, et al. (2012) β-Arrestin2 mediates the initiation and progression of myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 109: 12532-7
Xiao K, Sun J, Kim J, et al. (2012) Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464
Hara MR, Kovacs JJ, Whalen EJ, et al. (2011) A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53
Lovgren AK, Kovacs JJ, Xie T, et al. (2011) β-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. Science Translational Medicine. 3: 74ra23
Xiao K, Sun J, Kim J, et al. (2010) Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304
Kovacs JJ, Hara MR, Davenport CL, et al. (2009) Arrestin development: emerging roles for beta-arrestins in developmental signaling pathways. Developmental Cell. 17: 443-58
Walters RW, Shukla AK, Kovacs JJ, et al. (2009) beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. The Journal of Clinical Investigation. 119: 1312-21
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