Nathan L. Alderson, Ph.D.

Affiliations: 
2007 Medical University of South Carolina, Charleston, SC, United States 
Area:
Biochemistry, Neuroscience Biology
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"Nathan Alderson"
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Parents

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Hiroko Hama grad student 2007 MUSC
 (FA2H dependent fatty acid 2 -hydroxylation in the mammalian nervous system.)
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Publications

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Alderson NL, Hama H. (2009) Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. Journal of Lipid Research. 50: 1203-8
Ponnusamy S, Alderson NL, Hama H, et al. (2008) Regulation of telomere length by fatty acid elongase 3 in yeast. Involvement of inositol phosphate metabolism and Ku70/80 function. The Journal of Biological Chemistry. 283: 27514-24
Maldonado EN, Alderson NL, Monje PV, et al. (2008) FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelin. Journal of Lipid Research. 49: 153-61
Uchida Y, Hama H, Alderson NL, et al. (2007) Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation. The Journal of Biological Chemistry. 282: 13211-9
Vasireddy V, Uchida Y, Salem N, et al. (2007) Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death. Human Molecular Genetics. 16: 471-82
Alderson NL, Maldonado EN, Kern MJ, et al. (2006) FA2H-dependent fatty acid 2-hydroxylation in postnatal mouse brain. Journal of Lipid Research. 47: 2772-80
Alderson NL, Wang Y, Blatnik M, et al. (2006) S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate. Archives of Biochemistry and Biophysics. 450: 1-8
Alderson NL, Walla MD, Hama H. (2005) A novel method for the measurement of in vitro fatty acid 2-hydroxylase activity by gas chromatography-mass spectrometry. Journal of Lipid Research. 46: 1569-75
Januszewski AS, Alderson NL, Jenkins AJ, et al. (2005) Chemical modification of proteins during peroxidation of phospholipids. Journal of Lipid Research. 46: 1440-9
Alderson NL, Rembiesa BM, Walla MD, et al. (2004) The human FA2H gene encodes a fatty acid 2-hydroxylase. The Journal of Biological Chemistry. 279: 48562-8
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