Adrian R. Krainer

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
mRNA splicing
"Adrian Krainer"

Developed the first in vitro RNA splicing reactions using HeLa nuclear extract.

Mean distance: 15.14 (cluster 18)


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Qiang Wu grad student 1994-1998
Javier F. Caceres post-doc CSHL
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Nomakuchi TT, Rigo F, Aznarez I, et al. (2015) Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nature Biotechnology
Guo Y, Xu Q, Canzio D, et al. (2015) CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 162: 900-10
Chen HH, Welling M, Bloch DB, et al. (2014) DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 3: 892-904
Das S, Krainer AR. (2014) Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer. Molecular Cancer Research : McR. 12: 1195-204
Jensen MA, Wilkinson JE, Krainer AR. (2014) Splicing factor SRSF6 promotes hyperplasia of sensitized skin. Nature Structural & Molecular Biology. 21: 189-97
Sahashi K, Ling KK, Hua Y, et al. (2013) Pathological impact of SMN2 mis-splicing in adult SMA mice. Embo Molecular Medicine. 5: 1586-601
Cléry A, Sinha R, Anczuków O, et al. (2013) Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition. Proceedings of the National Academy of Sciences of the United States of America. 110: E2802-11
Das S, Fregoso OI, Krainer AR. (2013) A new path to oncogene-induced senescence: at the crossroads of splicing and translation. Cell Cycle (Georgetown, Tex.). 12: 1477-9
Wu J, Anczuków O, Krainer AR, et al. (2013) OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds. Nucleic Acids Research. 41: 5149-63
Fregoso OI, Das S, Akerman M, et al. (2013) Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence. Molecular Cell. 50: 56-66
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