Young-Don Kwak, Ph.D.

Affiliations: 
2006 University of Central Florida, Orlando, FL, United States 
Area:
Molecular Biology, Neuroscience Biology
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"Young-Don Kwak"
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Kiminobu Sugaya grad student 2006 University of Central Florida
 (Studies on the novel function of amyloid precursor protein in glial differentiation of neural stem cells.)
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Publications

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Lavado A, Park JY, Paré J, et al. (2018) The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Developmental Cell. 47: 576-591.e8
Kwak YD, Hendrix BJ, Sugaya K. (2014) Secreted type of amyloid precursor protein induces glial differentiation by stimulating the BMP/Smad signaling pathway. Biochemical and Biophysical Research Communications. 447: 394-9
Wang R, Li JJ, Diao S, et al. (2013) Metabolic stress modulates Alzheimer's β-secretase gene transcription via SIRT1-PPARγ-PGC-1 in neurons. Cell Metabolism. 17: 685-94
Kwak YD, Wang R, Li JJ, et al. (2011) Differential regulation of BACE1 expression by oxidative and nitrosative signals. Molecular Neurodegeneration. 6: 17
Kwak YD, Marutle A, Dantuma E, et al. (2011) Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation. European Journal of Pharmacology. 650: 18-27
Kwak YD, Dantuma E, Merchant S, et al. (2010) Amyloid-β precursor protein induces glial differentiation of neural progenitor cells by activation of the IL-6/gp130 signaling pathway. Neurotoxicity Research. 18: 328-38
Sugaya K, Kwak YD, Ohmitsu O, et al. (2007) Practical issues in stem cell therapy for Alzheimer's disease. Current Alzheimer Research. 4: 370-7
Sugaya K, Alvarez A, Marutle A, et al. (2006) Stem cell strategies for Alzheimer's disease therapy. Panminerva Medica. 48: 87-96
Kwak YD, Brannen CL, Qu T, et al. (2006) Amyloid precursor protein regulates differentiation of human neural stem cells. Stem Cells and Development. 15: 381-9
Kwak YD, Choumkina E, Sugaya K. (2006) Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells. Biochemical and Biophysical Research Communications. 344: 431-7
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