Paul L. Prather

Affiliations: 
University of Arkansas for Medical Sciences, United States 
Area:
Pharmacology, Neuroscience Biology
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"Paul Prather"
Mean distance: 21373.2
 

Children

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Jennifer Shoemaker grad student 2007 UAMS
Kathryn A. Seely grad student 2009 UAMS
Maheswari Rajasekaran grad student 2011 UAMS
Lisa K. Brents grad student 2013 UAMS

Collaborators

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William E. Fantegrossi collaborator 2009- UAMS
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Publications

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Janganati V, Salazar P, Parks BJ, et al. (2023) Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats. Frontiers in Pharmacology. 14: 1123261
Cabanlong CV, Russell LN, Fantegrossi WE, et al. (2022) Metabolites of Synthetic Cannabinoid 5F-MDMB-PINACA Retain Affinity, Act as High Efficacy Agonists and Exhibit Atypical Pharmacodynamic Properties at CB1 Receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology
Penthala NR, Shoeib A, Dachavaram SS, et al. (2020) 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 30: 127501
Pinson A, Yarbrough AL, Bush JM, et al. (2020) Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity. Pharmacology, Biochemistry, and Behavior. 172949
Jones S, Yarbrough AL, Fantegrossi WE, et al. (2020) Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135). Pharmacology Research & Perspectives. 8: e00561
Ford BM, Cabanlong CV, Tai S, et al. (2019) Reduced tolerance and asymmetrical cross-tolerance to effects of indole quinuclidinone analogue PNR-4-20, a G protein biased CB1R agonist in mice: comparisons with Δ9-THC and JWH-018. The Journal of Pharmacology and Experimental Therapeutics
Jones S, Yarbrough AL, Shoeib A, et al. (2019) Enzymatic Analysis of Glucuronidation of Synthetic Cannabinoid 1-Naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-25
Yarbrough AL, Pinson A, Prather PL, et al. (2019) Oxidative Metabolism and Comparative Analysis of Synthetic Cannabinoid N-(1-adamantyl)-1-(5-fluoropentyl)indazole-3-carboxamide (5F-AKB-48) and the Unfluorinated Analog AKB-48 The Faseb Journal. 33
Yarbrough A, Fujiwara R, Fantegrossi W, et al. (2019) Oxidative metabolism of synthetic cannabinoid STS-135 by recombinant P450S and human liver microsomes Drug Metabolism and Pharmacokinetics. 34: S28
Hutchison RD, Ford BM, Franks LN, et al. (2018) Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ-THC. Frontiers in Pharmacology. 9: 1084
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