James J. Hickman

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Neuroscience Biology
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"James Hickman"
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Publications

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Oleaga C, Bridges LR, Persaud K, et al. (2020) A functional long-term 2D serum-free human hepatic in vitro system for drug evaluation. Biotechnology Progress. e3069
Caneus J, Akanda N, Rumsey JW, et al. (2020) A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ and tau-induced pathophysiological effects on long-term potentiation. Alzheimer's & Dementia (New York, N. Y.). 6: e12029
Najjar SA, Smith AST, Long CJ, et al. (2019) A multiplexed in vitro assay system for evaluating human skeletal muscle functionality in response to drug treatment. Biotechnology and Bioengineering
McAleer CW, Pointon A, Long CJ, et al. (2019) On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships. Scientific Reports. 9: 9619
McAleer CW, Long CJ, Elbrecht D, et al. (2019) Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics. Science Translational Medicine. 11
Gonzalez M, Guo X, Lin M, et al. (2019) Polarity Induced in Human Stem Cell Derived Motoneurons on Patterned Self-Assembled Monolayers. Acs Chemical Neuroscience
Caneus J, Rumsey JW, Guo X, et al. (2019) P2-077: HIPSC-DERIVED CORTICAL NEURON HUMAN-ON-A-CHIP SYSTEM TO STUDY Aβ- AND TAU-INDUCED NEUROTOXICITIES IN ALZHEIMER'S DISEASE WITH AN IMPLICATION FOR DRUG DISCOVERY Alzheimers & Dementia. 15
Natarajan A, Smith AST, Berry B, et al. (2018) Temporal Characterization of Neuronal Migration Behavior on Chemically Patterned Neuronal Circuits in a Defined Environment. Acs Biomaterials Science & Engineering. 4: 3460-3470
Oleaga C, Riu A, Rothemund S, et al. (2018) Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system. Biomaterials. 182: 176-190
Berry BJ, Smith AST, Long CJ, et al. (2018) Physiological Aβ concentrations produce a more biomimetic representation of the Alzheimer's disease phenotype in iPSC derived human neurons. Acs Chemical Neuroscience
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