Kathryn A. Seely, Ph.D.

Affiliations: 
2009 University of Arkansas for Medical Sciences, United States 
Area:
Pharmacology, Neuroscience Biology
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"Kathryn Seely"
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Parents

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Paul L. Prather grad student 2009 UAMS
 (Cannabinoid receptor inverse agonists as novel therapeutic agents.)
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Publications

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Patton AL, Seely KA, Yarbrough AL, et al. (2018) Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants. Biochemical and Biophysical Research Communications
Pfannkoch EA, Stuff JR, Whitecavage JA, et al. (2015) A High Throughput Method for Measuring Polycyclic Aromatic Hydrocarbons in Seafood Using QuEChERS Extraction and SBSE. International Journal of Analytical Chemistry. 2015: 359629
Patton AL, Seely KA, Pulla S, et al. (2014) Quantitative measurement of acetyl fentanyl and acetyl norfentanyl in human urine by LC-MS/MS. Analytical Chemistry. 86: 1760-6
Seely KA, Patton AL, Moran CL, et al. (2013) Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds. Forensic Science International. 233: 416-22
Patton AL, Seely KA, Chimalakonda KC, et al. (2013) Targeted metabolomic approach for assessing human synthetic cannabinoid exposure and pharmacology. Analytical Chemistry. 85: 9390-9
Chimalakonda KC, Seely KA, Bratton SM, et al. (2012) Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 2174-84
Seely KA, Brents LK, Franks LN, et al. (2012) AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: Implications for opioid/cannabinoid interaction studies Neuropharmacology. 63: 905-915
Seely KA, Lapoint J, Moran JH, et al. (2012) Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 39: 234-43
Seely KA, Brents LK, Radominska-Pandya A, et al. (2012) A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Chemical Research in Toxicology. 25: 825-7
Brents LK, Medina-Bolivar F, Seely KA, et al. (2012) Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 42: 139-56
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