Kathryn E. Medders, Ph.D.

Affiliations: 
2010 Molecular Pathology University of California, San Diego, La Jolla, CA 
Area:
Neuroscience Biology, Molecular Biology
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"Kathryn Medders"
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Parents

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Marcus Kaul grad student 2010 UCSD
 (Molecular mechanisms of HIV gp120-induced neurotoxicity.)
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Publications

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Yuan NY, Medders KE, Sanchez AB, et al. (2024) A critical role for Macrophage-derived Cysteinyl-Leukotrienes in HIV-1 induced neuronal injury. Brain, Behavior, and Immunity. 118: 149-166
Sanchez AB, Medders KE, Maung R, et al. (2016) CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and L-type Ca(2+) channels upstream of p38 MAPK. Journal of Neuroinflammation. 13: 252
Maung R, Hoefer MM, Sanchez AB, et al. (2014) CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120. Journal of Immunology (Baltimore, Md. : 1950). 193: 1895-910
Maung R, Medders KE, Sejbuk NE, et al. (2012) Genetic knockouts suggest a critical role for HIV co-receptors in models of HIV gp120-induced brain injury. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 306-18
Medders KE, Kaul M. (2011) Mitogen-activated protein kinase p38 in HIV infection and associated brain injury. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 202-15
Medders KE, Sejbuk NE, Maung R, et al. (2010) Activation of p38 MAPK is required in monocytic and neuronal cells for HIV glycoprotein 120-induced neurotoxicity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4883-95
Kaul M, Ma Q, Medders KE, et al. (2007) HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death and Differentiation. 14: 296-305
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