Christopher James Donnelly, Ph.D.

Neurology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
"Christopher Donnelly"
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Jeffery L. Twiss grad student 2011 University of Delaware
 (mRNA localization and the fate of the axon.)
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Otte CG, Fortuna TR, Mann JR, et al. (2020) Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo. Neurobiology of Disease. 105078
Ortega JA, Daley EL, Kour S, et al. (2020) Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron
Casci I, Krishnamurthy K, Kour S, et al. (2019) Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. Nature Communications. 10: 5583
Mann JR, Gleixner AM, Mauna JC, et al. (2019) RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron
Zhang K, Donnelly CJ, Haeusler AR, et al. (2015) The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 525: 56-61
Donnelly CJ, Grima JC, Sattler R. (2014) Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets? Neurodegenerative Disease Management. 4: 417-37
Haeusler AR, Donnelly CJ, Periz G, et al. (2014) C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200
Donnelly CJ, Zhang PW, Pham JT, et al. (2013) RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28
Yoo S, Kim HH, Kim P, et al. (2013) A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element. Journal of Neurochemistry. 126: 792-804
Donnelly CJ, Park M, Spillane M, et al. (2013) Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3311-22
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