Jianzheng Zheng, Ph.D.

Affiliations: 
2010 Biomedical Sciences University of New Mexico, Albuquerque, NM, United States 
Area:
Pathology, Neuroscience Biology
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"Jianzheng Zheng"
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Parents

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Oscar A. Bizzozero grad student 2010 Univ. of New Mexico
 (An impaired 20S proteasome contributes to the accumulation of oxidized proteins in multiple sclerosis and its animal model.)
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Publications

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Smerjac SM, Zheng J, Hu CL, et al. (2018) The Role of Calpain and Proteasomes in the Degradation of Carbonylated Neuronal Cytoskeletal Proteins in Acute Experimental Autoimmune Encephalomyelitis. Neurochemical Research
Zheng J, Hu CL, Shanley KL, et al. (2017) Mechanism of Protein Carbonylation in Glutathione-Depleted Rat Brain Slices. Neurochemical Research
Morales-Pantoja IE, Hu CL, Perrone-Bizzozero NI, et al. (2016) Nrf2-dysregulation correlates with reduced synthesis and low glutathione levels in experimental autoimmune encephalomyelitis. Journal of Neurochemistry
Dasgupta A, Zheng J, Perrone-Bizzozero NI, et al. (2013) Increased carbonylation, protein aggregation and apoptosis in the spinal cord of mice with experimental autoimmune encephalomyelitis. Asn Neuro. 5: e00111
Dasgupta A, Zheng J, Bizzozero OA. (2012) Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion. Asn Neuro. 4
Zheng J, Dasgupta A, Bizzozero OA. (2012) Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 121: 486-94
Zheng J, Bizzozero OA. (2011) Decreased activity of the 20S proteasome in the brain white matter and gray matter of patients with multiple sclerosis. Journal of Neurochemistry. 117: 143-53
Zheng J, Bizzozero OA. (2010) Reduced proteasomal activity contributes to the accumulation of carbonylated proteins in chronic experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 115: 1556-67
Zheng J, Bizzozero OA. (2010) Accumulation of protein carbonyls within cerebellar astrocytes in murine experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 88: 3376-85
Zheng J, Bizzozero OA. (2010) Traditional reactive carbonyl scavengers do not prevent the carbonylation of brain proteins induced by acute glutathione depletion. Free Radical Research. 44: 258-66
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