Dhasakumar Navaratnam

Yale University, New Haven, CT 
Neuroscience Biology, Cell Biology, Genetics
"Dhasakumar Navaratnam"
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Bai JP, Navaratnam D, Santos-Sacchi J. (2019) Prestin kinetics and corresponding frequency dependence augment during early development of the outer hair cell within the mouse organ of Corti. Scientific Reports. 9: 16460
Zhong S, Rivera-Molina F, Rivetta A, et al. (2018) Seeing the long tail: A novel green fluorescent protein, SiriusGFP, for ultra long timelapse imaging. Journal of Neuroscience Methods
Tan W, Song L, Graham M, et al. (2017) Novel role of the mitochondrial protein Fus1 in protection from premature hearing loss via regulation of oxidative stress and nutrient and energy sensing pathways in the inner ear. Antioxidants & Redox Signaling
Zhang Y, Moeini-Naghani I, Bai J, et al. (2015) Tyrosine motifs are required for prestin basolateral membrane targeting. Biology Open. 4: 197-205
Zhong S, Navaratnam D, Santos-Sacchi J. (2014) A genetically-encoded YFP sensor with enhanced chloride sensitivity, photostability and reduced ph interference demonstrates augmented transmembrane chloride movement by gerbil prestin (SLC26a5). Plos One. 9: e99095
Bian S, Navaratnam D, Santos-Sacchi J. (2013) Real time measures of prestin charge and fluorescence during plasma membrane trafficking reveal sub-tetrameric activity. Plos One. 8: e66078
Li X, Surguchev A, Bian S, et al. (2012) Extracellular chloride regulation of Kv2.1, contributor to the major outward Kv current in mammalian outer hair cells. American Journal of Physiology. Cell Physiology. 302: C296-306
Frucht CS, Uduman M, Kleinstein SH, et al. (2011) Gene expression gradients along the tonotopic axis of the chicken auditory epithelium. Journal of the Association For Research in Otolaryngology : Jaro. 12: 423-35
Frucht CS, Santos-Sacchi J, Navaratnam DS. (2011) MicroRNA181a plays a key role in hair cell regeneration in the avian auditory epithelium. Neuroscience Letters. 493: 44-8
Bai JP, Surguchev A, Bian S, et al. (2010) Combinatorial cysteine mutagenesis reveals a critical intramonomer role for cysteines in prestin voltage sensing. Biophysical Journal. 99: 85-94
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