Joaquin Espinosa

Affiliations: 
Molecular, Cellular and Developmental Biology University of Colorado, Boulder, Boulder, CO, United States 
Area:
Human Development, Molecular Biology, Neuroscience Biology
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"Joaquin Espinosa"
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Publications

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Cozzolino K, Sanford L, Hunter S, et al. (2023) Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome. Biorxiv : the Preprint Server For Biology
Ludwig MP, Galbraith MD, Eduthan NP, et al. (2023) Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway. Cancer Research
Szwarc MM, Guarnieri AL, Joshi M, et al. (2023) FAM193A is a positive regulator of p53 activity. Cell Reports. 42: 112230
Tatavosian R, Donovan MG, Galbraith MD, et al. (2023) Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation. Cell Death and Differentiation
Donovan MG, Galbraith MD, Espinosa JM. (2022) Multi-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology. Scientific Reports. 12: 22505
Andrysik Z, Sullivan KD, Kieft JS, et al. (2022) PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response. Nature Communications. 13: 7400
Galbraith MD, Andrysik Z, Sullivan KD, et al. (2021) Global Analyses to Identify Direct Transcriptional Targets of p53. Methods in Molecular Biology (Clifton, N.J.). 2267: 19-56
Andrysik Z, Bender H, Galbraith MD, et al. (2021) Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. Nature Communications. 12: 1375
Rizzotto D, Zaccara S, Rossi A, et al. (2020) Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30. Cell Reports. 30: 4355-4369.e6
Steinparzer I, Sedlyarov V, Rubin JD, et al. (2019) Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions. Molecular Cell
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