Christoph Lepper, Ph.D.

2010 Johns Hopkins University, Baltimore, MD 
Cell Biology, General Biology
"Christoph Lepper"
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Chen-Ming Fan grad student 2010 Johns Hopkins
 (Pax7 positive satellite cells: Stem cells for skeletal muscle regeneration.)
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Li L, Rozo M, Yue S, et al. (2019) Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice. Nature Metabolism. 1: 985-995
Southard S, Low S, Li L, et al. (2014) A series of Cre-ER(T2) drivers for manipulation of the skeletal muscle lineage. Genesis (New York, N.Y. : 2000). 52: 759-70
Blum JM, Añó L, Li Z, et al. (2013) Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells. Cell Reports. 5: 933-40
Günther S, Kim J, Kostin S, et al. (2013) Myf5-positive satellite cells contribute to Pax7-dependent long-term maintenance of adult muscle stem cells. Cell Stem Cell. 13: 590-601
Lee SJ, Huynh TV, Lee YS, et al. (2012) Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 109: E2353-60
Fan CM, Li L, Rozo ME, et al. (2012) Making skeletal muscle from progenitor and stem cells: development versus regeneration. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 315-27
Lepper C, Fan CM. (2012) Generating tamoxifen-inducible Cre alleles to investigate myogenesis in mice. Methods in Molecular Biology (Clifton, N.J.). 798: 297-308
Lepper C, Partridge TA, Fan CM. (2011) An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development (Cambridge, England). 138: 3639-46
Lepper C, Fan CM. (2010) Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells. Genesis (New York, N.Y. : 2000). 48: 424-36
Lepper C, Conway SJ, Fan CM. (2009) Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements. Nature. 460: 627-31
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