Ismail Syed, Ph.D.

Affiliations: 
Medicine Harvard Medical School, Boston, MA, United States 
 2011 Pharmaceutical Sciences Wayne State University, Detroit, MI, United States 
Area:
Pharmacy, Pharmacology
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Parents

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Anjaneyulu Kowluru grad student 2011 Wayne State
 (Mechanisms of regulation of islet function by NADPH oxidase.)
Barbara B. Kahn post-doc Harvard Medical School
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Publications

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Rubin de Celis MF, Garcia-Martin R, Syed I, et al. (2022) PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206923119
Aryal P, Syed I, Lee J, et al. (2021) Distinct Biological Activities of Isomers from Different Families of Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs). Journal of Lipid Research. 100108
Syed I, Rubinde Celis MF, Mohan JF, et al. (2019) PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice. The Journal of Clinical Investigation. 129
SYED I, DE CELIS MFR, MOHAN JF, et al. (2019) 361-OR: ER Stress Attenuation Is Involved in PAHSA-Induced Reduction of T1D in Nonobese Diabetic (NOD) Mice Diabetes. 68: 361-OR
Hammarstedt A, Syed I, Vijayakumar A, et al. (2018) Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids. Scientific Reports. 8: 15757
Syed I, Lee J, Peroni OD, et al. (2018) Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects. Cell Metabolism
Syed I, Lee J, Moraes-Vieira PM, et al. (2018) Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metabolism. 27: 419-427.e4
SANTORO A, ZHOU P, PERONI OD, et al. (2018) Palmitic Acid Esters of Hydroxy Stearic Acids Are Hepatic Insulin Sensitizers in Chow and High-Fat Diet (HFD)–Fed Mice Diabetes. 67: 1838-P
Vijayakumar A, Aryal P, Wen J, et al. (2017) Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport. Cell Reports. 21: 1021-1035
Nelson AT, Kolar MJ, Chu Q, et al. (2017) Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation. Journal of the American Chemical Society
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