Melissa J. Alldred, Ph.D.

Affiliations: 
2005 Pennsylvania State University, State College, PA, United States 
Area:
Neuroscience Biology
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"Melissa Alldred"
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Bernhard Luscher grad student 2005 Penn State
 (An investigation of the domains of the gamma two subunit of GABA(A) receptors, gephyrin and collybistin required for synaptic localization.)
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Publications

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Gautier MK, Kelley CM, Lee SH, et al. (2023) Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of down syndrome and Alzheimer's disease. Neurobiology of Disease. 106332
Alldred MJ, Pidikiti H, Heguy A, et al. (2023) Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22944
Alldred MJ, Lee SH, Stutzmann GE, et al. (2021) Oxidative Phosphorylation Is Dysregulated Within the Basocortical Circuit in a 6-month old Mouse Model of Down Syndrome and Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 707950
Alldred MJ, Lee SH, Ginsberg SD. (2021) Adiponectin Modulation by Genotype and Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer's Disease. Journal of Clinical Medicine. 10
Alldred MJ, Penikalapati SC, Lee SH, et al. (2021) Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease. Molecular Neurobiology
Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, et al. (2019) Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology. Neurobiology of Disease. 104540
Alldred MJ, Chao HM, Lee SH, et al. (2019) Long-term effects of maternal choline supplementation on CA1 pyramidal neuron gene expression in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802669RR
Kelley CM, Ginsberg SD, Alldred MJ, et al. (2019) Maternal choline supplementation alters basal forebrain cholinergic neuron gene expression in the Ts65Dn mouse model of Down syndrome. Developmental Neurobiology
Perez SE, Miguel JC, He B, et al. (2019) Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia. Acta Neuropathologica
Peng KY, Pérez-González R, Alldred MJ, et al. (2018) Apolipoprotein E4 genotype compromises brain exosome production. Brain : a Journal of Neurology
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