Anita A. Mathias, Ph.D.

Affiliations: 
2004 University of Washington, Seattle, Seattle, WA 
Area:
Pharmacy, Obstetrics and Gynecology
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Parents

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Jashvant D. Unadkat grad student 2004 University of Washington
 (Disposition of anti -HIV protease inhibitors in pregnancy.)
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Publications

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Kirby BJ, Lutz JD, Yue MS, et al. (2020) OATP Inhibition Dramatically Increases Plasma Exposure, but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure, of Firsocostat. Clinical Pharmacology and Therapeutics
Kumar V, Yin M, Ishida K, et al. (2020) Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Reyes M, Lutz JD, Lau AH, et al. (2020) Safety, pharmacokinetics and pharmacodynamics of selgantolimod, an oral Toll-like receptor 8 agonist: a Phase Ia study in healthy subjects. Antiviral Therapy
Humeniuk R, Mathias A, Cao H, et al. (2020) Safety, Tolerability, and Pharmacokinetics of Remdesivir, an Antiviral for Treatment of COVID-19, in Healthy Subjects. Clinical and Translational Science
Meng A, Anderson K, Nelson C, et al. (2020) Sat0149 Exposure-Response Relationships For Efficacy And Safety Of Filgotinib And Its Metabolite Gs-829845 In Subjects With Rheumatoid Arthritis Based On Phase 2 And Phase 3 Studies Annals of the Rheumatic Diseases. 79: 1013-1014
Kumar V, Ishida K, Salphati L, et al. (2020) P129 - In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes Drug Metabolism and Pharmacokinetics. 35
Anderson K, Xin Y, Zheng H, et al. (2019) Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects. Clinical Pharmacology in Drug Development
Kumar V, Salphati L, Hop CECA, et al. (2019) A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes vs. Human Liver Tissue Using Quantitative Targeted Proteomics and Cell-Surface Biotinylation. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Begley R, Meng A, Massetto B, et al. (2019) IDDF2019-ABS-0135 Pharmacokinetics of once-daily sofosbuvir or ledipasvir/sofosbuvir in HCV-infected pediatrics aged 3 to Gut. 68
Anderson K, Zheng H, Medzihradsky O, et al. (2019) Thu0117 Pharmacokinetics And Short-Term Safety Of Filgotinib, A Selective Janus Kinase 1 Inhibitor, In Subjects With Moderate Hepatic Impairment Annals of the Rheumatic Diseases. 78: 331-331
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