Peng Hsiao, Ph.D.

Affiliations: 
2011 University of Washington, Seattle, Seattle, WA 
Area:
Pharmacy, Neuroscience Biology, Cell Biology
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"Peng Hsiao"
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Parents

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Jashvant D. Unadkat grad student 2011 University of Washington
 (Can P-glycoprotein-Based Drug Interactions at the Human Blood-Brain Barrier be Predicted from In Vitro and Rat In Vivo studies?)
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Publications

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Liu L, Collier AC, Link JM, et al. (2015) Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1795-804
Deo AK, Borson S, Link JM, et al. (2014) Activity of P-Glycoprotein, a β-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1106-11
Hsiao P, Unadkat JD. (2014) Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies. Molecular Pharmaceutics. 11: 436-44
Lai Y, Hsiao P. (2014) Beyond the ITC White Paper: emerging sciences in drug transporters and opportunities for drug development. Current Pharmaceutical Design. 20: 1577-94
Hsiao P, Unadkat JD. (2012) P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans. Molecular Pharmaceutics. 9: 629-33
Deo A, Borson S, Link J, et al. (2012) Activity of P-glycoprotein, an ABC efflux transporter at the blood-brain barrier, is compromised in Alzheimer's disease Alzheimers & Dementia. 8: 698
Chung FS, Eyal S, Muzi M, et al. (2010) Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate. British Journal of Pharmacology. 159: 394-404
Eyal S, Hsiao P, Unadkat JD. (2009) Drug interactions at the blood-brain barrier: fact or fantasy? Pharmacology & Therapeutics. 123: 80-104
Hsiao P, Bui T, Ho RJ, et al. (2008) In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 481-4
Hsiao P, Sasongko L, Link JM, et al. (2006) Verapamil P-glycoprotein transport across the rat blood-brain barrier: cyclosporine, a concentration inhibition analysis, and comparison with human data. The Journal of Pharmacology and Experimental Therapeutics. 317: 704-10
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