Pierre-Luc Tanguay, Ph.D.

Affiliations: 
2011 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology
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"Pierre-Luc Tanguay"

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Sylvain Meloche grad student 2011 Université de Montréal
 (Implication de la voie ERK3/4-MK5 dans la phase G2/M du cycle cellulaire.)
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Publications

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Pelletier B, Duhamel S, Tambutet G, et al. (2023) Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen. Acs Chemical Biology
Soulez M, Tanguay PL, Dô F, et al. (2022) ERK3-MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation. Journal of Cellular Physiology
Guégan JP, Lapouge M, Voisin L, et al. (2022) Signaling by the tyrosine kinase Yes promotes liver cancer development. Science Signaling. 15: eabj4743
Duhamel S, Girondel C, Dorn JF, et al. (2016) Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway. Cell Cycle (Georgetown, Tex.). 0
Déléris P, Trost M, Topisirovic I, et al. (2011) Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway. The Journal of Biological Chemistry. 286: 6470-8
Tanguay PL, Rodier G, Meloche S. (2010) C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis. The Biochemical Journal. 428: 103-11
Boutonnet C, Tanguay PL, Julien C, et al. (2010) Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2. Cell Cycle (Georgetown, Tex.). 9: 975-9
Granados DP, Tanguay PL, Hardy MP, et al. (2009) ER stress affects processing of MHC class I-associated peptides. Bmc Immunology. 10: 10
Déléris P, Rousseau J, Coulombe P, et al. (2008) Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. Journal of Cellular Physiology. 217: 778-88
Rodier G, Coulombe P, Tanguay PL, et al. (2008) Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase. The Embo Journal. 27: 679-91
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