Jose D. Vela

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
pain, adrenergics
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"Jose Vela"
Mean distance: 16.35 (cluster 32)
 
SNBCP

Parents

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Ken M. Hargreaves grad student 2003-2008 UT Health San Antonio
 (Beta adrenergic modulation of peripheral nociceptors.)
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Publications

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Díaz JL, Christmann U, Fernández A, et al. (2015) Synthesis and structure-activity relationship study of a new series of selective σ(1) receptor ligands for the treatment of pain: 4-aminotriazoles. Journal of Medicinal Chemistry. 58: 2441-51
Rodríguez-Muñoz M, Sánchez-Blázquez P, Herrero-Labrador R, et al. (2015) The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control. Antioxidants & Redox Signaling. 22: 799-818
Mazo I, Roza C, Zamanillo D, et al. (2015) Effects of centrally acting analgesics on spinal segmental reflexes and wind-up. European Journal of Pain (London, England). 19: 1012-20
Almansa C, Vela JM. (2014) Selective sigma-1 receptor antagonists for the treatment of pain. Future Medicinal Chemistry. 6: 1179-99
Gris G, Merlos M, Vela JM, et al. (2014) S1RA, a selective sigma-1 receptor antagonist, inhibits inflammatory pain in the carrageenan and complete Freund's adjuvant models in mice. Behavioural Pharmacology. 25: 226-35
Nieto FR, Cendán CM, Cañizares FJ, et al. (2014) Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice. Molecular Pain. 10: 11
Vidal-Torres A, Fernández-Pastor B, Carceller A, et al. (2014) Effects of the selective sigma-1 receptor antagonist S1RA on formalin-induced pain behavior and neurotransmitter release in the spinal cord in rats. Journal of Neurochemistry. 129: 484-94
Gómez-Soler M, Fernández-Dueñas V, Portillo-Salido E, et al. (2014) Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor. Journal of Medicinal Chemistry. 57: 238-42
Vidal-Torres A, de la Puente B, Rocasalbas M, et al. (2013) Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects. European Journal of Pharmacology. 711: 63-72
Díaz JL, Christmann U, Fernández A, et al. (2013) Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands. Journal of Medicinal Chemistry. 56: 3656-65
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