William L. Dewey

Affiliations: 
Virginia Commonwealth University School of Medicine, Richmond, VA 
Area:
pharmacology, analgesics, opioids
Google:
"William Dewey"
Mean distance: 16.04 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

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Publications

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Obeng S, Jali A, Zheng Y, et al. (2019) Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment. Acs Chemical Neuroscience
Zheng Y, Obeng S, Wang H, et al. (2019) Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'- pyridyl)carboxamido]morphinan (NAP) Derivatives as Mu/Kappa Opioid Receptor Dual Selective Ligands. Journal of Medicinal Chemistry
Poklis JL, Gonek MM, Wolf CE, et al. (2018) Analysis of carbenoxolone by ultra-performance liquid chromatography tandem mass spectrometry in mouse brain and blood after systemic administration. Biomedical Chromatography : Bmc. e4465
Obeng S, Wang H, Jali A, et al. (2018) Structure activity relationship studies of 6α- and 6β-indolylacetamidonaltrexamine derivatives as bitopic mu opioid receptor modulators and elaboration of the 'message-address concept' to comprehend their functional conversion. Acs Chemical Neuroscience
Zheng Y, Obeng S, Wang H, et al. (2018) Methylation Products of 6β-N-heterocyclic substituted naltrexamine derivatives as potential peripheral opioid receptor modulators. Acs Chemical Neuroscience
Jacob JC, Poklis JL, Akbarali HI, et al. (2017) Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone. The Journal of Pharmacology and Experimental Therapeutics
Xu GG, Zolotarskaya OY, Williams DA, et al. (2017) Nanoconjugated NAP as a Potent and Periphery Selective Mu Opioid Receptor Modulator To Treat Opioid-Induced Constipation. Acs Medicinal Chemistry Letters. 8: 78-83
Xu X, Zhang A, Halquist MS, et al. (2016) Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages. Journal of Cellular and Molecular Medicine
Williams DA, Zheng Y, David BG, et al. (2016) 6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand. Acs Chemical Neuroscience
Xu X, Yuan X, Li N, et al. (2016) Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice. Journal of Cellular and Molecular Medicine
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