Anastasios Georgakopoulos
Affiliations: | Genetics and Genomic Sciences | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
Neuroscience Biology, AgingGoogle:
"Anastasios Georgakopoulos"Mean distance: 106866
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Publications
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| Yoon Y, Voloudakis G, Doran N, et al. (2020) PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Molecular Psychiatry |
| Warren NA, Voloudakis G, Yoon Y, et al. (2018) The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis. Cellular and Molecular Life Sciences : Cmls |
| Huang Q, Voloudakis G, Ren Y, et al. (2017) Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Nikolakopoulou AM, Georgakopoulos A, Robakis NK. (2016) Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations. Neurobiology of Aging. 42: 41-9 |
| Moreno JL, Miranda-Azpiazu P, García-Bea A, et al. (2016) Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia. Science Signaling. 9: ra5 |
| Bruban J, Voloudakis G, Huang Q, et al. (2015) Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Robakis NK, Georgakopoulos A. (2014) Allelic interference: a mechanism for trans-dominant transmission of loss of function in the neurodegeneration of familial Alzheimer's disease. Neuro-Degenerative Diseases. 13: 126-30 |
| Xuan Z, Barthet G, Shioi J, et al. (2013) Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B. The Journal of Biological Chemistry. 288: 30495-501 |
| Barthet G, Dunys J, Shao Z, et al. (2013) Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors. Neurobiology of Aging. 34: 499-510 |
| Barthet G, Georgakopoulos A, Robakis NK. (2012) Cellular mechanisms of γ-secretase substrate selection, processing and toxicity. Progress in Neurobiology. 98: 166-75 |