Sarah V. Bradley, Ph.D.

Affiliations: 
2010 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Oncology
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"Sarah Bradley"
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Parents

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Theodora S. Ross grad student 2010 University of Michigan
 (The role of huntingtin interacting protein 1 (HIP1) in tumorigenesis.)
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Publications

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Graves CW, Philips ST, Bradley SV, et al. (2008) Use of a cryptic splice site for the expression of huntingtin interacting protein 1 in select normal and neoplastic tissues. Cancer Research. 68: 1064-73
Bradley SV, Smith MR, Hyun TS, et al. (2007) Aberrant Huntingtin interacting protein 1 in lymphoid malignancies. Cancer Research. 67: 8923-31
Bradley SV, Hyun TS, Oravecz-Wilson KI, et al. (2007) Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. Human Molecular Genetics. 16: 1279-92
Bradley SV, Holland EC, Liu GY, et al. (2007) Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor. Cancer Research. 67: 3609-15
Smith MR, Joshi I, Jin F, et al. (2006) Role of Huntingtin Interacting Protein HIP-1 in Non-Hodgkin’s Lymphoma. Blood. 108: 2384-2384
Bradley SV, Oravecz-Wilson KI, Bougeard G, et al. (2005) Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer. Cancer Research. 65: 4126-33
Kalli KR, Bradley SV, Fuchshuber S, et al. (2004) Estrogen receptor-positive human epithelial ovarian carcinoma cells respond to the antitumor drug suramin with increased proliferation: possible insight into ER and epidermal growth factor signaling interactions in ovarian cancer. Gynecologic Oncology. 94: 705-12
Hyun TS, Li L, Oravecz-Wilson KI, et al. (2004) Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Molecular and Cellular Biology. 24: 4329-40
Hyun TS, Rao DS, Saint-Dic D, et al. (2004) HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains. The Journal of Biological Chemistry. 279: 14294-306
Rao DS, Bradley SV, Kumar PD, et al. (2003) Altered receptor trafficking in Huntingtin Interacting Protein 1-transformed cells. Cancer Cell. 3: 471-82
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