Aaron Peng, Ph.D.

Affiliations: 
2011 Pharmaceutical Sciences State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Pharmacy, Pharmacology
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Sathy V. Balu-Iyer grad student 2011 SUNY Buffalo
 (Phosphatidylinositol reduces the immunogenicity and clearance of human recombinant factor VIII in hemophilia a mice.)
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Peng A, Kosloski MP, Nakamura G, et al. (2012) PEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice. The Aaps Journal. 14: 35-42
Peng A, Pisal DS, Doty A, et al. (2012) Phosphatidylinositol induces fluid phase formation and packing defects in phosphatidylcholine model membranes. Chemistry and Physics of Lipids. 165: 15-22
Gaitonde P, Peng A, Straubinger RM, et al. (2012) Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIII. Journal of Pharmaceutical Sciences. 101: 48-55
Kosloski MP, Peng A, Varma PR, et al. (2011) Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates. Drug Delivery. 18: 246-54
Gaitonde P, Peng A, Straubinger RM, et al. (2011) Phosphatidylserine reduces immune response against human recombinant Factor VIII in Hemophilia A mice by regulation of dendritic cell function. Clinical Immunology (Orlando, Fla.). 138: 135-45
Peng A, Straubinger RM, Balu-Iyer SV. (2010) Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice. The Aaps Journal. 12: 473-81
Peng A, Gaitonde P, Kosloski MP, et al. (2009) Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice. Journal of Pharmaceutical Sciences. 98: 4480-4
Miclea RD, Varma PR, Peng A, et al. (2007) Development and characterization of lipidic cochleate containing recombinant factor VIII. Biochimica Et Biophysica Acta. 1768: 2890-8
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