Thomas F. Gamage

Affiliations: 
2008-2014 Pharmacology and Toxicology Virginia Commonwealth University, Richmond, VA, United States 
 2014-2016 Center for Substance Abuse Research Temple University, Philadelphia, PA, United States 
 2016- Analytical Chemistry and Pharmaceutics RTI International 
Area:
molecular and behavioral pharmacology, allosteric modulation, cannabinoids, opioids, drug abuse, dependence
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"Thomas Gamage"
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Parents

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Jenny L. Wiley grad student 2008-2009 VCU
Aron H. Lichtman grad student 2009-2014 VCU
 (Differential effects of endocannabinoid catabolic inhibitors on opioid withdrawal in mice.)
Brian F. Thomas post-doc 2016- RTI International
Mary E. Abood post-doc 2014-2016 Temple University (Cell Biology Tree)
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Publications

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Wiley JL, Marusich JA, Blough BE, et al. (2024) Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 132: 110984
Marusich JA, Gamage TF, Zhang Y, et al. (2022) In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists. Pharmacology, Biochemistry, and Behavior. 220: 173467
Finlay DB, Nguyen T, Gamage TF, et al. (2022) Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018. Pharmacology Research & Perspectives. 10: e00901
Nguyen T, Gamage TF, Decker AM, et al. (2021) Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids. Bioorganic & Medicinal Chemistry. 41: 116215
Wiley JL, Barrus DG, Farquhar CE, et al. (2020) Sex, species and age: Effects of rodent demographics on the pharmacology of ∆-tetrahydrocanabinol. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110064
Gamage TF, Barrus DG, Kevin RC, et al. (2020) In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018. Pharmacology, Biochemistry, and Behavior. 172918
Nguyen T, Gamage T, Decker AM, et al. (2019) Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators. Journal of Medicinal Chemistry
Kevin RC, Kovach AL, Lefever TW, et al. (2019) Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures. Forensic Toxicology. 37: 17-26
Gamage TF, Farquhar CE, McKinnie RJ, et al. (2018) Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics
Farquhar CE, Breivogel CS, Gamage TF, et al. (2018) Sex, THC, and hormones: Effects on density and sensitivity of CB cannabinoid receptors in rats. Drug and Alcohol Dependence. 194: 20-27
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