Graham M. Pitcher

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Pain
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"Graham Pitcher"
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SNBCP

Parents

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Terence J. Coderre grad student McGill
James L. Henry grad student 2000 McGill
 (Eicosanoid mediation/modulation in spinal nociceptive mechanisms in the normal rat and in a rat model of chronic pain.)
Michael W. Salter post-doc 2000-2006 Hospital for Sick Children
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Publications

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Hildebrand ME, Pitcher GM, Harding EK, et al. (2014) GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord. Scientific Reports. 4: 4094
Pitcher GM, Ritchie J, Henry JL. (2013) Peripheral neuropathy induces cutaneous hypersensitivity in chronically spinalized rats. Pain Medicine (Malden, Mass.). 14: 1057-71
Salter MW, Pitcher GM. (2012) Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia. The Febs Journal. 279: 2-11
Pitcher GM, Kalia LV, Ng D, et al. (2011) Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors. Nature Medicine. 17: 470-8
Ng D, Pitcher GM, Szilard RK, et al. (2009) Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. Plos Biology. 7: e41
Pitcher GM, Henry JL. (2008) Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy. Experimental Neurology. 214: 219-28
Pitcher GM, Beggs S, Woo RS, et al. (2008) ErbB4 is a suppressor of long-term potentiation in the adult hippocampus. Neuroreport. 19: 139-43
Kalia LV, Pitcher GM, Pelkey KA, et al. (2006) PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex. The Embo Journal. 25: 4971-82
Pitcher GM, Henry JL. (2004) Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain. Experimental Neurology. 186: 173-97
Ma L, Huang YZ, Pitcher GM, et al. (2003) Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3164-75
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