Ryan Jefferson Watts

Affiliations: 
Genentech, San Francisco, CA, United States 
Area:
Neurodegeneration, Blood-brian barrier
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"Ryan Watts"
Mean distance: 14.77 (cluster 11)
 
SNBCP

Parents

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Liqun Luo grad student 2004 Stanford
 (Cellular and molecular mechanisms of developmental axon pruning.)

Children

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Nga Bien-Ly post-doc Genentech
Stephen Tam post-doc Elan
Gregory B. Potter research scientist 2015-2018
BETA: Related publications

Publications

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Liao F, Li A, Xiong M, et al. (2018) Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. The Journal of Clinical Investigation
Lee SH, Le Pichon CE, Adolfsson O, et al. (2016) Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Reports
Lu Y, Hoyte K, Montgomery WH, et al. (2016) Characterization of a sensitive mouse Aβ40 PD biomarker assay for Alzheimer's disease drug development in wild-type mice. Bioanalysis
Gadkar K, Yadav DB, Zuchero JY, et al. (2016) Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
Zuchero YJ, Chen X, Bien-Ly N, et al. (2015) Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron
Bien-Ly N, Boswell CA, Jeet S, et al. (2015) Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron. 88: 289-97
Fuji RN, Flagella M, Baca M, et al. (2015) Effect of selective LRRK2 kinase inhibition on nonhuman primate lung. Science Translational Medicine. 7: 273ra15
Watts RJ. (2014) Sleeping our Alzheimer's risk away. The Journal of Experimental Medicine. 211: 2484-5
Wetzel-Smith MK, Hunkapiller J, Bhangale TR, et al. (2014) A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7
Huntley MA, Bien-Ly N, Daneman R, et al. (2014) Dissecting gene expression at the blood-brain barrier. Frontiers in Neuroscience. 8: 355
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