John Wilkie, Ph.D.
Affiliations: | Chemistry | University of Birmingham, UK, Birmingham, England, United Kingdom |
Area:
Computational Bio-organic ChemistryWebsite:
http://www.birmingham.ac.uk/staff/profiles/chemistry/wilkie-john.aspxGoogle:
"John Wilkie"Mean distance: 9.13 | S | N | B | C | P |
Parents
Sign in to add mentor| Colin Thomson | grad student | 1983-1987 | University of St Andrews |
| Ian H. Williams | post-doc | 1990-1993 | University of Bath (United Kingdom) |
| David Gani | post-doc | 1993-1998 | University of St Andrews, Scotland, UK |
Children
Sign in to add trainee| Shina Caroline Lynn Kamerlin | grad student | University of Birmingham, UK |
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Publications
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| Kamerlin SC, Wilkie J. (2011) The effect of leaving group on mechanistic preference in phosphate monoester hydrolysis. Organic & Biomolecular Chemistry. 9: 5394-406 |
| Christofferson A, Wilkie J. (2009) Mechanism of CB1954 reduction by Escherichia coli nitroreductase. Biochemical Society Transactions. 37: 413-8 |
| Kamerlin SC, Wilkie J. (2007) The role of metal ions in phosphate ester hydrolysis. Organic & Biomolecular Chemistry. 5: 2098-108 |
| Rutherford TJ, Wilkie J, Vu CQ, et al. (2001) NMR studies and semi-empirical energy calculations for cyclic ADP-ribose. Nucleosides, Nucleotides & Nucleic Acids. 20: 1485-95 |
| Belloni M, Manickam M, Ashton PR, et al. (2001) The X-ray crystal structures and computational analysis of NH...π hydrogen bonded banana-shaped carbazole derivatives and thermal analysis of higher mesogenic homologues Molecular Crystals and Liquid Crystals Science and Technology Section a: Molecular Crystals and Liquid Crystals. 369: 17-35 |
| Miller DJ, Beaton MW, Wilkie J, et al. (2000) The 6-OH group of D-inositol 1-phosphate serves as an H-bond donor in the catalytic hydrolysis of the phosphate ester by inositol monophosphatase. Chembiochem : a European Journal of Chemical Biology. 1: 262-71 |
| Ryan MD, Donnelly M, Lewis A, et al. (1999) A model for nonstoichiometric, cotranslational protein scission in eukaryotic ribosomes Bioorganic Chemistry. 27: 55-79 |
| Schulz J, Wilkie J, Beaton MW, et al. (1998) Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol monophosphatase reaction. Biochemical Society Transactions. 26: 315-22 |
| Lewis A, Rutherford TJ, Wilkie J, et al. (1998) Design, construction and properties of peptide N-terminal cap templates devised to initiate α-helices. Part 3. Caps derived from N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2R)-Ala-(2S,4S)-4-thioPro-OMe Journal of the Chemical Society - Perkin Transactions 1. 3795-3806 |
| Gani D, Lewis A, Rutherford T, et al. (1998) Design, synthesis, structure and properties of an α-helix cap template derived from N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2R)-Ala-(2S,4S)-4-thioPro- OMe which initiates α-helical structures Tetrahedron. 54: 15793-15819 |