☰ Chemistry Tree

Amy Christine Anderson

Affiliations:

Medicinal Chemistry

University of Connecticut, Storrs, CT, United States

Area:

X-Ray crystallography, Structural biology, Molecular modeling, Structure-based drug design

Website:

http://pharmsci.uconn.edu/?p=871

Google:

Bio:

http://homepages.uconn.edu/~ama05016/Personnel2.html

Mean distance: 8.78

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Cross-listing: Crystallography Tree

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Parents

Christin A. Frederick	grad student	1997	Harvard
(A crystallographic study of RNA motifs)
Robert M. Stroud	post-doc	1997-2000	UCSF

Children

Stephanie M. Reeve	grad student		University of Connecticut
Jennifer M. Beierlein	grad student	2011	University of Connecticut
Kathleen M. Frey	grad student	2011	University of Connecticut
Janet L. Paulsen	grad student	2012	University of Connecticut
Sophia N. Ononye	grad student	2013	University of Connecticut

Collaborators

BETA: Related publications

Publications

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Krucinska J, Falcone E, Erlandsen H, et al. (2019) Structural and Functional Studies of Bacterial Enolase, a Potential Target Against Gram-Negative Pathogens. Biochemistry
Cammarata M, Thyer R, Lombardo M, et al. (2017) Characterization of trimethoprim resistant dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates. Chemical Science. 8: 4062-4072
Hoody J, Alverson JB, Keshipeddy S, et al. (2017) Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1051: 54-59
Ojewole A, Lowegard A, Gainza P, et al. (2017) OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design. Methods in Molecular Biology (Clifton, N.J.). 1529: 291-306
G-Dayanandan N, Scocchera EW, Keshipeddy S, et al. (2016) Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks. Organic Letters
Reeve SM, Scocchera EW, G-Dayanadan N, et al. (2016) MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates. Cell Chemical Biology
Li J, Falcone ER, Holstein SA, et al. (2016) Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis. Pharmacological Research
Lombardo MN, G-Dayanandan N, Wright DL, et al. (2016) Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates. Acs Infectious Diseases. 2: 149-56
Hajian B, Scocchera E, Keshipeddy S, et al. (2016) Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Plos One. 11: e0161740
Scocchera E, Reeve SM, Keshipeddy S, et al. (2016) Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens. Acs Medicinal Chemistry Letters. 7: 692-6

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