Esther Fride, PhD

Affiliations: 
NIH (NIDDK) 
Area:
pharmacology, neurobiology, neuroimmunology, neonatal insults and stress, endocannabinoids
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"Esther Fride"
Bio:

Ester Fride, PhD (1953-2010)
Dr. Fride was born in 1953, in Amsterdam. She was the daughter of German refugees and survivors from the Holocaust. She moved to Israel at age 19 After getting a PhD in neurobiology from the medical school at Hebrew University of Jerusalem, she then did research in the U.S. at Johns Hopkins and the National Institutes of Health (Phil Skolnick, PhD) on how Prenatal stress affects an infant’s brain.
In 1990, she returned to Israel and began work in the lab of Raphael Mechoulam, where their focus was on cannabinoids and their effects in the body. Her most notable discoveries were in the endocannabinoid system and nursing. The endocannabinoid system helps regulate our sleep, appetite, mood, memory and the effects of cannabis. Her findings helped shape future cannabis research and placed a wider importance on a healthy endocannabinoid system.
Dr. Fride passed prematurely in 2010.

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Publications

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Schechter M, Pinhasov A, Weller A, et al. (2012) Blocking the postpartum mouse dam's CB1 receptors impairs maternal behavior as well as offspring development and their adult social-emotional behavior. Behavioural Brain Research. 226: 481-92
Bregman T, Fride E. (2011) Behavioral alterations in cystic fibrosis mice are prevented by cannabinoid treatment in infancy. Journal of Basic and Clinical Physiology and Pharmacology. 22: 33-6
Bregman T, Fride E. (2011) Treatment with tetrahydrocannabinol (THC) prevents infertility in male cystic fibrosis mice. Journal of Basic and Clinical Physiology and Pharmacology. 22: 29-32
Fride E, Gobshtis N, Dahan H, et al. (2009) The endocannabinoid system during development: emphasis on perinatal events and delayed effects. Vitamins and Hormones. 81: 139-58
Schroeder M, Schechter M, Fride E, et al. (2009) Examining maternal influence on OLETF rats' early overweight: insights from a cross-fostering study. Developmental Psychobiology. 51: 358-66
Patinkin D, Milman G, Breuer A, et al. (2008) Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation European Journal of Pharmacology. 595: 1-6
Moussaieff A, Rimmerman N, Bregman T, et al. (2008) Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34
Fride E. (2008) Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal development. Journal of Neuroendocrinology. 20: 75-81
Moussaieff A, Shohami E, Kashman Y, et al. (2007) Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation. Molecular Pharmacology. 72: 1657-64
Fride E, Braun H, Matan H, et al. (2007) Inhibition of milk ingestion and growth after administration of a neutral cannabinoid CB1 receptor antagonist on the first postnatal day in the mouse. Pediatric Research. 62: 533-6
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