Robert R. Rando, Ph.D.
Affiliations: | Biological Chemistry and Molecular Pharmacology | Harvard Medical School, Boston, MA, United States |
Area:
Biochemistry of VisionGoogle:
"Robert Rando"Mean distance: 17.83 (cluster 32) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| William von Eggers Doering | grad student | 1967 | Yale (Chemistry Tree) | |
| (The intramolecular carbene reaction) | ||||
| Konrad Bloch | post-doc | Harvard | ||
Children
Sign in to add trainee| Yulong Chen | post-doc | Harvard Medical School | |
| Do Hyun Ryu | post-doc | Harvard Medical School (Chemistry Tree) |
BETA: Related publications
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Publications
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| Xue L, Jahng WJ, Gollapalli D, et al. (2006) Palmitoyl transferase activity of lecithin retinol acyl transferase. Biochemistry. 45: 10710-8 |
| Maiti P, Gollapalli D, Rando RR. (2005) Specificity of binding of all-trans-retinyl ester to RPE65. Biochemistry. 44: 14463-9 |
| Fishkin N, Yefidoff R, Gollipalli DR, et al. (2005) On the mechanism of isomerization of all-trans-retinol esters to 11-cis-retinol in retinal pigment epithelial cells: 11-fluoro-all-trans-retinol as substrate/inhibitor in the visual cycle. Bioorganic & Medicinal Chemistry. 13: 5189-94 |
| Gollapalli DR, Rando RR. (2004) The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 101: 10030-5 |
| Xue L, Gollapalli DR, Maiti P, et al. (2004) A palmitoylation switch mechanism in the regulation of the visual cycle. Cell. 117: 761-71 |
| Xue L, Rando RR. (2004) Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism. Biochemistry. 43: 6120-6 |
| Gollapalli DR, Rando RR. (2003) Molecular logic of 11-cis-retinoid biosynthesis in a cone-dominated species. Biochemistry. 42: 14921-9 |
| Jahng WJ, Xue L, Rando RR. (2003) Lecithin retinol acyltransferase is a founder member of a novel family of enzymes. Biochemistry. 42: 12805-12 |
| Gollapalli DR, Maiti P, Rando RR. (2003) RPE65 operates in the vertebrate visual cycle by stereospecifically binding all-trans-retinyl esters. Biochemistry. 42: 11824-30 |
| Gollapalli DR, Rando RR. (2003) Specific inactivation of isomerohydrolase activity by 11-cis-retinoids. Biochimica Et Biophysica Acta. 1651: 93-101 |