Demetrius Moskophidis

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Genetics, Cell Biology, Molecular Biology
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"Demetrius Moskophidis"
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Publications

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Eroglu B, Pang J, Jin X, et al. (2019) HSF1-mediated Control of Cellular Energy Metabolism and mTORC1 Activation Drive Acute T Cell Lymphoblastic Leukemia Progression. Molecular Cancer Research : McR
Cho W, Jin X, Pang J, et al. (2019) The Molecular Chaperone HSP70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA-Damage and MAPK/ERK Signaling Pathways. Molecular and Cellular Biology
Jin X, Qiao A, Moskophidis D, et al. (2018) Modulation of HSF1 Activity Through Silencing of Ser303/Ser307 Phosphorylation Supports A Metabolic Program Leading to Age-related Obesity and Insulin Resistance. Molecular and Cellular Biology
Jin X, Qiao A, Moskophidis D, et al. (2017) Abrogation of heat shock factor 1 (Hsf1) phosphorylation deregulates its activity and lowers activation threshold, leading to obesity in mice. The Journal of Biological Chemistry
Qiao A, Jin X, Pang J, et al. (2017) The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. The Journal of Cell Biology
Jin X, Moskophidis D, Hu Y, et al. (2009) Heat shock factor 1 deficiency via its downstream target gene alphaB-crystallin (Hspb5) impairs p53 degradation. Journal of Cellular Biochemistry. 107: 504-15
Chen M, Lan S, Ou R, et al. (2008) Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system. The Journal of General Virology. 89: 1421-33
Ou R, Zhang M, Huang L, et al. (2008) Regulation of immune response and inflammatory reactions against viral infection by VCAM-1. Journal of Virology. 82: 2952-65
Ou R, Zhang M, Huang L, et al. (2008) Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection. Journal of Virology. 82: 3353-68
Huang L, Min JN, Masters S, et al. (2007) Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis (New York, N.Y. : 2000). 45: 487-501
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