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Brian K. Kobilka

Affiliations: 
Molecular & Cellular Physiology Stanford University, Palo Alto, CA 
Area:
Adrenergic receptors
Website:
http://med.stanford.edu/kobilkalab/index.html
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"Brian Kobilka"
Bio:

The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"

Mean distance: 14.61 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree - Physiology Academic Tree

Parents

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Robert J. Lefkowitz post-doc 1984-1989 Duke

Children

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Yoon Seok Kim grad student 2015- Stanford
Pejman Ghanouni grad student 2001 Stanford (Chemistry Tree)
Thomas P. Finsterbach grad student 2007 Stanford (Chemistry Tree)
Carl M. Hurt grad student 2007 Stanford (Chemistry Tree)
Juan J. Fung grad student 2009 Stanford (Chemistry Tree)
Hideaki E. Kato post-doc Stanford School of Medicine (Chemistry Tree)
Daniel M. Rosenbaum post-doc Stanford (Chemistry Tree)
Mark von Zastrow post-doc Stanford Medical School
John Janetzko post-doc 2017- Stanford Medical School (Chemistry Tree)
Haoqing Wang post-doc 2019- Stanford (Chemistry Tree)
Uwe Klein post-doc 1995-1998 Stanford
Peter Nollert post-doc 1999-2001 Stanford (Chemistry Tree)
Ka Young Chung post-doc 2008-2011 Stanford
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Publications

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Wei TT, Chandy M, Nishiga M, et al. (2022) Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell. 185: 2387-2389
Janetzko J, Kise R, Barsi-Rhyne B, et al. (2022) Membrane Phosphoinositides Stabilize GPCR-arrestin Complexes and Provide Temporal Control of Complex Assembly and Dynamics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Gmeiner P, Wang H, Hetzer F, et al. (2022) Structure-based Evolution of G protein-biased μ-opioid Receptor Agonists. Angewandte Chemie (International Ed. in English)
Sun B, Willard FS, Feng D, et al. (2022) Structural determinants of dual incretin receptor agonism by tirzepatide. Proceedings of the National Academy of Sciences of the United States of America. 119: e2116506119
Ghani L, Kim S, Wang H, et al. (2022) Foldable detergents for membrane protein study: Importance of detergent core flexibility in protein stabilization. Chemistry (Weinheim An Der Bergstrasse, Germany)
Utz PJ, Jain MK, Cheung VG, et al. (2022) Translating science to medicine: The case for physician-scientists. Science Translational Medicine. 14: eabg7852
Ehsan M, Wang H, Katsube S, et al. (2022) Glyco-steroidal amphiphiles (GSAs) for membrane protein structural study. Chembiochem : a European Journal of Chemical Biology
Tsutsumi N, Maeda S, Qu Q, et al. (2022) Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins. Science Advances. 8: eabl5442
Li Y, Heng J, Sun D, et al. (2021) Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor β-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus. Journal of the American Chemical Society. 143: 17566-17576
Heyder NA, Kleinau G, Speck D, et al. (2021) Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell Research
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