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Brian K. Kobilka

Affiliations: 
Molecular & Cellular Physiology Stanford University, Palo Alto, CA 
Area:
Adrenergic receptors
Website:
http://med.stanford.edu/kobilkalab/index.html
Google:
"Brian Kobilka"
Bio:

The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"

Mean distance: 14.61 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree - Physiology Academic Tree

Parents

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Robert M. Carlson research assistant University of Minnesota Duluth (Chemistry Tree)
Conrad E. Firling research assistant University of Minnesota Duluth (Physiology Academic Tree)
 (A medium for the maintenance of Chironomus tentans salivary glands in vitro.)
Robert J. Lefkowitz post-doc 1984-1989 Duke

Children

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Andrew Kruse grad student Stanford (Chemistry Tree)
Aashish Manglik grad student Stanford (Chemistry Tree)
Yoon Seok Kim grad student 2015- Stanford
Pejman Ghanouni grad student 2001 Stanford (Chemistry Tree)
Thomas P. Finsterbach grad student 2007 Stanford (Chemistry Tree)
Carl M. Hurt grad student 2007 Stanford (Chemistry Tree)
Juan J. Fung grad student 2009 Stanford (Chemistry Tree)
Daniel Hilger post-doc Stanford (Chemistry Tree)
Søren G.F. Rasmussen post-doc Stanford (Chemistry Tree)
Daniel M. Rosenbaum post-doc Stanford (Chemistry Tree)
Mark von Zastrow post-doc Stanford Medical School
John Janetzko post-doc 2017- Stanford Medical School (Chemistry Tree)
Haoqing Wang post-doc 2019- Stanford (Chemistry Tree)
Uwe Klein post-doc 1995-1998 Stanford
Peter Nollert post-doc 1999-2001 Stanford (Chemistry Tree)
Ka Young Chung post-doc 2008-2011 Stanford
Hideaki E. Kato post-doc 2014-2019 Stanford School of Medicine (Chemistry Tree)
BETA: Related publications

Publications

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Toyoda Y, Zhu A, Kong F, et al. (2023) Structural basis of α-adrenergic receptor activation and recognition by an extracellular nanobody. Nature Communications. 14: 3655
Zhao J, Elgeti M, O'Brien ES, et al. (2023) Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. Biorxiv : the Preprint Server For Biology
Krishna Kumar K, Robertson MJ, Thadhani E, et al. (2023) Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672
Xu X, Shonberg J, Kaindl J, et al. (2023) Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138
Heng J, Hu Y, Pérez-Hernández G, et al. (2023) Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. Nature Communications. 14: 2005
Krishna Kumar K, O'Brien ES, Habrian CH, et al. (2023) Negative allosteric modulation of the glucagon receptor by RAMP2. Cell. 186: 1465-1477.e18
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, et al. (2023) Time-resolved cryo-EM of G protein activation by a GPCR. Biorxiv : the Preprint Server For Biology
Xu J, Wang Q, Hübner H, et al. (2023) Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature Communications. 14: 376
Faouzi A, Wang H, Zaidi SA, et al. (2022) Structure-based design of bitopic ligands for the µ-opioid receptor. Nature
Qu Q, Huang W, Aydin D, et al. (2022) Insights into distinct signaling profiles of the µOR activated by diverse agonists. Nature Chemical Biology
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