John D. Schuetz

Affiliations: 
Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Cell Biology, Physiology Biology
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"John Schuetz"
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Publications

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Gose T, Rasouli A, Dehghani-Ghahnaviyeh S, et al. (2024) Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 73: 101066
Gose T, Aitken HM, Wang Y, et al. (2023) The net electrostatic potential and hydration of ABCG2 affect substrate transport. Nature Communications. 14: 5035
Baril SA, Gose T, Schuetz JD. (2023) How Cryo-EM Has Expanded Our Understanding of Membrane Transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 51: 904-922
Lynch J, Wang Y, Li Y, et al. (2023) A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin. Communications Biology. 6: 673
Ganguly S, Finkelstein D, Shaw TI, et al. (2021) Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters. Plos One. 16: e0253852
Donepudi AC, Smith GJ, Aladelokun O, et al. (2020) Lack of multidrug-resistance associated protein 4 prolongs partial hepatectomy-induced hepatic steatosis. Toxicological Sciences : An Official Journal of the Society of Toxicology
Gose T, Shafi T, Fukuda Y, et al. (2020) ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Wijaya J, Vo BT, Liu J, et al. (2020) An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling. Cancer Research
Gose T, Shafi T, Fukuda Y, et al. (2020) A Single Amino Acid in ABCG2 is Essential for Clamping Substrates and Inhibitors into the Binding Pocket The Faseb Journal. 34: 1-1
Ford RC, Marshall-Sabey D, Schuetz J. (2019) Linker Domains: Why ABC Transporters 'Live in Fragments no Longer'. Trends in Biochemical Sciences
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