William J. Valentine, Ph.D.
Affiliations: | 2004 | University of Tennessee Health Science Center, Memphis, TN, United States |
Area:
Molecular Biology, PathologyGoogle:
"William Valentine"Parents
Sign in to add mentor| Lawrence Pfeffer | grad student | 2004 | UTHSC | |
| (Molecular characterization of STAT3.) | ||||
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Publications
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| Kiss GN, Lee SC, Fells JI, et al. (2013) Mitigation of radiation injury by selective stimulation of the LPA(2) receptor. Biochimica Et Biophysica Acta. 1831: 117-25 |
| Valentine WJ, Godwin VI, Osborne DA, et al. (2011) FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane domain 2. The Journal of Biological Chemistry. 286: 30513-25 |
| Valentine WJ, Kiss GN, Liu J, et al. (2010) (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity. Cellular Signalling. 22: 1543-53 |
| Lu X, Sun C, Valentine WJ, et al. (2009) Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720. The Journal of Organic Chemistry. 74: 3192-5 |
| Valentine WJ, Fells JI, Perygin DH, et al. (2008) Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors. The Journal of Biological Chemistry. 283: 12175-87 |
| Valentine WJ, Fujiwara Y, Tsukahara R, et al. (2008) Lysophospholipid signaling: beyond the EDGs. Biochimica Et Biophysica Acta. 1780: 597-605 |
| Yang CH, Wei L, Pfeffer SR, et al. (2007) Identification of CXCL11 as a STAT3-dependent gene induced by IFN. Journal of Immunology (Baltimore, Md. : 1950). 178: 986-92 |
| Moughal NA, Waters CM, Valentine WJ, et al. (2006) Protean agonism of the lysophosphatidic acid receptor-1 with Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells. Journal of Neurochemistry. 98: 1920-9 |
| Tsukahara T, Tsukahara R, Yasuda S, et al. (2006) Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma. The Journal of Biological Chemistry. 281: 3398-407 |
| Yang CH, Murti A, Valentine WJ, et al. (2005) Interferon alpha activates NF-kappaB in JAK1-deficient cells through a TYK2-dependent pathway. The Journal of Biological Chemistry. 280: 25849-53 |