Michael A. Matrone, Ph.D.

Affiliations: 
2009 Molecular Medicine University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Cell Biology
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"Michael Matrone"

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Stuart S. Martin grad student 2009 University of Maryland Medical School
 (The microtubule-associated protein tau induces microtentacle formation and the reattachment of detached and circulating tumor cells.)
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Publications

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Vitolo MI, Boggs AE, Whipple RA, et al. (2013) Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin. Oncogene. 32: 2200-10
Yoon JR, Whipple RA, Balzer EM, et al. (2011) Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells. Breast Cancer Research and Treatment. 129: 691-701
Balzer EM, Whipple RA, Thompson K, et al. (2010) c-Src differentially regulates the functions of microtentacles and invadopodia. Oncogene. 29: 6402-8
Matrone MA, Whipple RA, Balzer EM, et al. (2010) Microtentacles tip the balance of cytoskeletal forces in circulating tumor cells. Cancer Research. 70: 7737-41
Whipple RA, Matrone MA, Cho EH, et al. (2010) Epithelial-to-mesenchymal transition promotes tubulin detyrosination and microtentacles that enhance endothelial engagement. Cancer Research. 70: 8127-37
Matrone MA, Whipple RA, Thompson K, et al. (2010) Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells. Oncogene. 29: 3217-27
Cho EH, Whipple RA, Matrone MA, et al. (2010) Delocalization of gamma-tubulin due to increased solubility in human breast cancer cell lines. Cancer Biology & Therapy. 9: 66-76
Balzer EM, Whipple RA, Cho EH, et al. (2010) Antimitotic chemotherapeutics promote adhesive responses in detached and circulating tumor cells. Breast Cancer Research and Treatment. 121: 65-78
Balzer EM, Whipple-Bettes R, Cho EH, et al. (2010) Abstract 5133: Microtentacles and invadopodia: Functionally distinct plasma membrane protrusions of metastatic breast tumor cells separated mechanistically by c-Src Cancer Research. 70: 5133-5133
Whipple RA, Matrone MA, Cho EH, et al. (2010) Abstract 1464: EMT-induced tubulin detyrosination can be inhibited with parthenolide, reducing microtentacles and the lung retention of circulating breast tumor cells Cancer Research. 70: 1464-1464
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