Brian R. Rosborough, Ph.D.
Affiliations: | 2013 | Immunology | University of Pittsburgh, Pittsburgh, PA, United States |
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ImmunologyGoogle:
"Brian Rosborough"Parents
Sign in to add mentor| Angus W. Thomson | grad student | 2013 | University of Pittsburgh | |
| (Manipulation of regulatory myeloid cell differentiation and function and its therapeutic implications.) | ||||
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Publications
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| Yazdani HO, Chen HW, Tohme S, et al. (2017) IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation. Journal of Hepatology |
| Chen LC, Nicholson YT, Rosborough BR, et al. (2016) A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950) |
| Raïch-Regué D, Rosborough BR, Watson AR, et al. (2015) mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo. Journal of Immunology (Baltimore, Md. : 1950). 194: 4767-76 |
| Rosborough BR, Raïch-Regué D, Liu Q, et al. (2014) Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2173-80 |
| Matta BM, Lott JM, Mathews LR, et al. (2014) IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 4010-20 |
| Rosborough BR, Hackstein H, Turnquist HR. (2014) A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells. Kidney International. 85: 743-5 |
| Rosborough BR, Mathews LR, Matta BM, et al. (2014) Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 3470-3 |
| Huang H, Nace GW, McDonald KA, et al. (2014) Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection. Hepatology (Baltimore, Md.). 59: 1984-97 |
| Stenger EO, Rosborough BR, Mathews LR, et al. (2014) IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 192-201 |
| Rosborough BR, Raïch-Regué D, Turnquist HR, et al. (2014) Regulatory myeloid cells in transplantation. Transplantation. 97: 367-79 |