Makarand V. Risbud
Affiliations: | Cell and Developmental Biology | Thomas Jefferson University, Philadelphia, PA, United States |
Area:
Molecular Biology, Cell Biology, General BiologyGoogle:
"Makarand Risbud"
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Publications
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| Johnston SN, Tsingas M, Ain R, et al. (2023) Increased HIF-2α Activity in the Nucleus Pulposus Causes Intervertebral Disc Degeneration in the Aging Mouse Spine. Biorxiv : the Preprint Server For Biology |
| Johnston SN, Madhu V, Shapiro IM, et al. (2022) Conditional deletion of HIF-2α in mouse nucleus pulposus reduces fibrosis and provides mild and transient protection from age-dependent structural changes in intervertebral disc. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
| Ohnishi T, Novais EJ, Risbud MV. (2020) Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration. Matrix Biology Plus. 6: 100036 |
| Tsingas M, Ottone OK, Haseeb A, et al. (2020) Sox9 deletion causes severe intervertebral disc degeneration characterized by apoptosis, matrix remodeling, and compartment-specific transcriptomic changes. Matrix Biology : Journal of the International Society For Matrix Biology |
| Tessier S, Risbud MV. (2020) Understanding embryonic development for cell-based therapies of intervertebral disc degeneration: Towards an effort to treat disc degeneration subphenotypes. Developmental Dynamics : An Official Publication of the American Association of Anatomists |
| Novais EJ, Tran VA, Miao J, et al. (2020) Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging. Aging Cell |
| Madhu V, Boneski PK, Silagi E, et al. (2020) Hypoxic regulation of mitochondrial metabolism and mitophagy in nucleus pulposus cells is dependent on HIF-1α -BNIP3 axis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
| Tessier S, Doolittle AC, Sao K, et al. (2020) Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight |
| Gorth DJ, Ottone OK, Shapiro IM, et al. (2019) Differential effect of long-term systemic exposure of TNFα on health of the annulus fibrosus and nucleus pulposus of the intervertebral disc. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
| Tessier S, Tran VA, Ottone OK, et al. (2019) TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression. Matrix Biology : Journal of the International Society For Matrix Biology |