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Michael H. Hecht

Affiliations: 
Chemistry Princeton University, Princeton, NJ 
Area:
Synthetic Biology and Alzheimer's Disease
Website:
http://www.princeton.edu/chemistry/faculty/profiles/hecht/
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"Michael Hecht"
Bio:

http://www.princeton.edu/~hecht/hecht.html

Mean distance: 8.13
 
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Parents

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Harold Abraham Scheraga research assistant Cornell
Robert T. Sauer grad student 1984 MIT
 (The effect of amino acid replacement on the structure and stability of the N-terminal domain of the lambda repressor)
David C. Richardson post-doc 1990 Duke University Medical School
Jane S. Richardson post-doc 1990 Duke University Medical School

Children

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Sushmita Mimi Roy grad student 1992-1998 Princeton
Weixun Wang grad student 2001 Princeton
David A. Moffet grad student 2002 Princeton
Yinan Wei grad student 2003 Princeton
Aditi Das grad student 2005 Princeton
Woojin Kim grad student 2007 Princeton
Jermont Chen grad student 2008 Princeton
Abigail T. Go grad student 2008 Princeton
Shona C. Patel grad student 2008 Princeton
Angela F. McKoy grad student 2011 Princeton
Maria Korolev grad student 2013 Princeton
Kenric Joseph Hoegler grad student 2011-2016 Princeton
Luke H. Bradley post-doc 2001-2006 Princeton
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Publications

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Wang MS, Hecht MH. (2020) A Completely ATPase from Combinatorial Protein Design. Journal of the American Chemical Society. 142: 15230-15234
Mancini JA, Pike DH, Tyryshkin AM, et al. (2020) Design of a Fe S Cluster into the Core of a De Novo 4-Helix Bundle. Biotechnology and Applied Biochemistry
Zarzhitsky S, Jiang A, Stanley E, et al. (2020) Harnessing Synthetic Biology to Enhance Heterologous Protein Expression. Protein Science : a Publication of the Protein Society
Karas C, Hecht M. (2020) A Strategy for Combinatorial Cavity Design in De Novo Proteins. Life (Basel, Switzerland). 10
Kimura N, Mochizuki K, Umezawa K, et al. (2020) Hyperstable Protein with a Dimeric Bisecting Topology. Acs Synthetic Biology
Wang MS, Hoegler KJ, Hecht MH. (2019) Unevolved De Novo Proteins Have Innate Tendencies to Bind Transition Metals. Life (Basel, Switzerland). 9
Kobayashi N, Inano K, Sasahara K, et al. (2018) Self-Assembling Supramolecular Nanostructures Constructed from de Novo Extender Protein Nanobuilding Blocks. Acs Synthetic Biology
Hoegler KJ, Hecht MH. (2018) Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity. Journal of Molecular Evolution
Hecht MH, Zarzhitsky S, Karas C, et al. (2018) Are natural proteins special? Can we do that? Current Opinion in Structural Biology. 48: 124-132
Digianantonio KM, Korolev M, Hecht MH. (2017) A Non-Natural Protein Rescues Cells Deleted for a Key Enzyme in Central Metabolism. Acs Synthetic Biology
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