Ioana Abraham, Ph.D.

Affiliations: 
2012 St. John's University (New York), School of Pharmacy 
Area:
Pharmacology, Oncology
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"Ioana Abraham"

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Zhe-Sheng Chen grad student 2012 St. John's University (New York), School of Pharmacy
 (Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells.)
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Publications

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Abraham I, El Sayed K, Chen ZS, et al. (2012) Current status on marine products with reversal effect on cancer multidrug resistance. Marine Drugs. 10: 2312-21
Li T, Yang Y, Cheng C, et al. (2012) Design, synthesis and biological evaluation of N-arylphenyl-2,2-dichloroacetamide analogues as anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 22: 7268-71
Shi Z, Tiwari AK, Shukla S, et al. (2011) Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance. Cancer Research. 71: 3029-41
Tiwari AK, Shi Z, Shukla S, et al. (2011) Abstract 1739: Reversal of ABCB1- and ABCG2-mediated drug resistance by sildenafil Cancer Research. 71: 1739-1739
Abraham I, Jain S, Wu CP, et al. (2010) Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Biochemical Pharmacology. 80: 1497-506
Jain S, Abraham I, Carvalho P, et al. (2009) Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling. Journal of Natural Products. 72: 1291-8
Shi Z, Tiwari AK, Shukla S, et al. (2009) Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478. Biochemical Pharmacology. 77: 781-93
Shi Z, Jain S, Kim IW, et al. (2007) Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Cancer Science. 98: 1373-80
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