Tetsuo Uno
Affiliations: | GNF |
Area:
Protein medicinal chemistryGoogle:
"Tetsuo Uno"Mean distance: (not calculated yet)
Parents
Sign in to add mentorPeter G. Schultz | grad student | 1990-1996 | UC Berkeley |
Peter G. Schultz | research scientist | 2001-2010 | GNF |
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Publications
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Pham GH, Ou W, Bursulaya B, et al. (2018) Tuning a Protein Labeling Reaction to Achieve Highly Site-Selective Lysine Conjugation. Chembiochem : a European Journal of Chemical Biology |
Grunewald J, Jin Y, Vance J, et al. (2017) Optimization of an Enzymatic Antibody Drug Conjugation Approach based on CoA Analogs. Bioconjugate Chemistry |
Grunewald J, Klock HE, Cellitti SE, et al. (2015) Efficient preparation of site-specific antibody-drug conjugates using phosphopantetheinyl transferases. Bioconjugate Chemistry |
Grünewald J, Jones DH, Brock A, et al. (2014) Site-specific dual labeling of proteins by using small orthogonal tags at neutral pH. Chembiochem : a European Journal of Chemical Biology. 15: 1787-91 |
Marsilje TH, Pei W, Chen B, et al. (2013) Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials. Journal of Medicinal Chemistry. 56: 5675-90 |
Chiu HP, Grünewald J, Hao X, et al. (2012) Simultaneous purification and site-specific modification of pyrroline-carboxy-lysine proteins. Chembiochem : a European Journal of Chemical Biology. 13: 364-6 |
Ou W, Uno T, Chiu HP, et al. (2011) Site-specific protein modifications through pyrroline-carboxy-lysine residues. Proceedings of the National Academy of Sciences of the United States of America. 108: 10437-42 |
Cellitti SE, Ou W, Chiu HP, et al. (2011) D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine. Nature Chemical Biology. 7: 528-30 |
Jones DH, Cellitti SE, Hao X, et al. (2010) Site-specific labeling of proteins with NMR-active unnatural amino acids. Journal of Biomolecular Nmr. 46: 89-100 |
Sharif O, Hu H, Klock H, et al. (2009) Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4. Analytical Biochemistry. 392: 162-8 |