Gabriel Mitchell, Ph.D.

Affiliations: 
2012 Université de Sherbrooke, Sherbrooke, Québec, Canada 
Area:
General Biology
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"Gabriel Mitchell"

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Francois Malouin grad student 2012 Université de Sherbrooke
 (Contribution du regulon sigma B a la pathogenese de variants de Staphylococcus aureus formant de petites colonies lors d'infections pulmonaires chroniques chez les patients atteints de fibrose kystique.)
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Publications

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Mitchell G, Silvis MR, Talkington KC, et al. (2022) Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms. Mbio. e0272621
Boulanger S, Mitchell G, Bouarab K, et al. (2015) The Bactericidal Effect of the Tomatidine and Tobramycin Combination Against MRSA and Pseudomonas aeruginosa is Enhanced by Interspecific Small Molecule Interactions. Antimicrobial Agents and Chemotherapy
Chagnon F, Guay I, Bonin MA, et al. (2014) Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus. European Journal of Medicinal Chemistry. 80: 605-20
Fugère A, Lalonde Séguin D, Mitchell G, et al. (2014) Interspecific small molecule interactions between clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus from adult cystic fibrosis patients. Plos One. 9: e86705
Mitchell G, Fugère A, Pépin Gaudreau K, et al. (2013) SigB is a dominant regulator of virulence in Staphylococcus aureus small-colony variants. Plos One. 8: e65018
Mitchell G, Lafrance M, Boulanger S, et al. (2012) Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression. The Journal of Antimicrobial Chemotherapy. 67: 559-68
Mitchell G, Grondin G, Bilodeau G, et al. (2011) Infection of polarized airway epithelial cells by normal and small-colony variant strains of Staphylococcus aureus is increased in cells with abnormal cystic fibrosis transmembrane conductance regulator function and is influenced by NF-κB. Infection and Immunity. 79: 3541-51
Pruneau M, Mitchell G, Moisan H, et al. (2011) Transcriptional analysis of antibiotic resistance and virulence genes in multiresistant hospital-acquired MRSA. Fems Immunology and Medical Microbiology. 63: 54-64
Mitchell G, Gattuso M, Grondin G, et al. (2011) Tomatidine inhibits replication of Staphylococcus aureus small-colony variants in cystic fibrosis airway epithelial cells. Antimicrobial Agents and Chemotherapy. 55: 1937-45
Mitchell G, Lafrance M, Talbot BG, et al. (2011) Interleukin-6 and Interleukin-8 Secretions by Polarized Airway Epithelial Cells Infected by Normal and Small-Colony Variant Staphylococcus aureus Strains are Similar Despite Differences in Infection Levels Journal of Bacteriology & Parasitology. 2: 1-3
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