Savita Sankar, Ph.D.

Affiliations: 
2013 Oncological Sciences University of Utah, Salt Lake City, UT 
Area:
Oncology
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"Savita Sankar"

Parents

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Stephen L. Lessnick grad student 2013 University of Utah
 (Characterization of the mechanisms of transcriptional regulation by EWS/FLI in Ewing sarcoma.)
Kristen L. Kroll post-doc 2014-2017 Washington University School of Medicine (Neurotree)
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Publications

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Lewis EMA, Sankar S, Tong C, et al. (2020) Geminin is required for Hox gene regulation to pattern the developing limb. Developmental Biology
Sankar S, Patterson E, Lewis EM, et al. (2017) Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors. Genes & Cancer. 8: 725-744
Zhang B, Madden P, Gu J, et al. (2017) Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues. Bmc Genomics. 18: 439
Sankar S, Yellajoshyula D, Zhang B, et al. (2016) Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1. Scientific Reports. 6: 37412
Sankar S, Bell R, Stephens B, et al. (2016) Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Oncogene
Osgood CL, Maloney N, Kidd CG, et al. (2016) Identification of mithramycin analogs with improved targeting of the EWS-FLI1 transcription factor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Zhuo R, Kosak KM, Sankar S, et al. (2014) Targeting Glutathione S-transferase M4 in Ewing sarcoma. Frontiers in Pediatrics. 2: 83
Sankar S, Theisen ER, Bearss J, et al. (2014) Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4584-97
Zhuo R, Kosak KM, Sankar S, et al. (2014) Abstract 3965: Modulating glutathione s-transferase M4 activity for the treatment of Ewing sarcoma Cancer Research. 74: 3965-3965
Theisen ER, Sankar S, Bearss J, et al. (2014) Abstract 3679: Inhibition of LSD1 disrupts global EWS/ETS transcriptional function in Ewing sarcoma Cancer Research. 74: 3679-3679
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