Adam D. Bachstetter

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Alzheimers disease, traumatic brain injury, neuroinflammation, microglia, neuron-glia interactions, signal transduction, cytokines
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Parents

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Paula C. Bickford grad student 2005-2009 University of South Florida
Daniel M. Watterson post-doc 2009-2010 (Chemistry Tree)
Linda J. Van Eldik post-doc 2009-2015
Peter T. Nelson post-doc 2013-2015
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Publications

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Braun DJ, Bachstetter AD, Sudduth TL, et al. (2019) Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia. Geroscience
Bodnar CN, Morganti JM, Bachstetter AD. (2018) Depression following a traumatic brain injury: uncovering cytokine dysregulation as a pathogenic mechanism. Neural Regeneration Research. 13: 1693-1704
Rowe RK, Harrison JL, Zhang H, et al. (2018) Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury. Journal of Neuroinflammation. 15: 154
Zhou Z, Bachstetter AD, Späni CB, et al. (2017) Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes. Journal of Neuroinflammation. 14: 75
Smith VD, Bachstetter AD, Ighodaro E, et al. (2017) Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi. Brain Pathology (Zurich, Switzerland)
Bachstetter AD, Ighodaro ET, Hassoun Y, et al. (2017) Rod-shaped microglia morphology is associated with aging in 2 human autopsy series. Neurobiology of Aging. 52: 98-105
Heneka M, Andreasson KI, Bachstetter AD, et al. (2016) Targeting innate immunity for neurodegenerative disorders of the central nervous system. Journal of Neurochemistry
Rowe RK, Ellis GI, Harrison JL, et al. (2016) Diffuse traumatic brain injury induces prolonged immune dysregulation and potentiates hyperalgesia following a peripheral immune challenge. Molecular Pain. 12
Bachstetter AD, Zhou Z, Rowe RK, et al. (2016) MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses. Plos One. 11: e0149451
Ighodaro ET, Abner EL, Fardo DW, et al. (2016) Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
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