Adam D. Bachstetter

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Alzheimers disease, traumatic brain injury, neuroinflammation, microglia, neuron-glia interactions, signal transduction, cytokines
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Parents

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Paula C. Bickford grad student 2005-2009 University of South Florida
Daniel M. Watterson post-doc 2009-2010 (Chemistry Tree)
Linda J. Van Eldik post-doc 2009-2015
Peter T. Nelson post-doc 2013-2015
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Publications

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Macheda T, Roberts KN, Morganti JM, et al. (2020) Optimization and validation of a modified radial-arm water maze protocol using a murine model of mild closed head traumatic brain injury. Plos One. 15: e0232862
Early AN, Gorman AA, Van Eldik LJ, et al. (2020) Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice. Journal of Neuroinflammation. 17: 115
Bachstetter AD, Morganti JM, Bodnar CN, et al. (2020) The effects of mild closed head injuries on tauopathy and cognitive deficits in rodents: Primary results in wild type and rTg4510 mice, and a systematic review. Experimental Neurology. 113180
Katsumata Y, Fardo DW, Bachstetter AD, et al. (2019) Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene. Journal of Neuropathology and Experimental Neurology
Braun DJ, Bachstetter AD, Sudduth TL, et al. (2019) Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia. Geroscience
Bodnar CN, Morganti JM, Bachstetter AD. (2018) Depression following a traumatic brain injury: uncovering cytokine dysregulation as a pathogenic mechanism. Neural Regeneration Research. 13: 1693-1704
Rowe RK, Harrison JL, Zhang H, et al. (2018) Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury. Journal of Neuroinflammation. 15: 154
Zhou Z, Bachstetter AD, Späni CB, et al. (2017) Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes. Journal of Neuroinflammation. 14: 75
Smith VD, Bachstetter AD, Ighodaro E, et al. (2017) Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi. Brain Pathology (Zurich, Switzerland)
Bachstetter AD, Ighodaro ET, Hassoun Y, et al. (2017) Rod-shaped microglia morphology is associated with aging in 2 human autopsy series. Neurobiology of Aging. 52: 98-105
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