Rafal P. Witek, Ph.D.

Affiliations: 
2005 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Cell Biology
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"Rafal Witek"
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Parents

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Bryon E. Petersen grad student 2005 University of Florida
 (Novel application of gene therapy and somatic stem cells in treating metabolic liver disorders.)
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Publications

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Pereira TA, Syn WK, Amâncio FF, et al. (2016) Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni. Plos Neglected Tropical Diseases. 10: e0005057
González-Mariscal I, Krzysik-Walker SM, Doyle ME, et al. (2016) Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism. Scientific Reports. 6: 33302
Pereira TA, Syn WK, MacHado MV, et al. (2015) Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni. Clinical Science (London, England : 1979)
Pereira TA, Xie G, Choi SS, et al. (2013) Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 149-61
LeCluyse EL, Witek RP, Andersen ME, et al. (2012) Organotypic liver culture models: meeting current challenges in toxicity testing. Critical Reviews in Toxicology. 42: 501-48
Jung Y, Oh SH, Witek RP, et al. (2012) Somatostatin stimulates the migration of hepatic oval cells in the injured rat liver. Liver International : Official Journal of the International Association For the Study of the Liver. 32: 312-20
Philips GM, Chan IS, Swiderska M, et al. (2011) Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. Plos One. 6: e23943
Choi SS, Syn WK, Karaca GF, et al. (2010) Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. The Journal of Biological Chemistry. 285: 36551-60
Pereira Tde A, Witek RP, Syn WK, et al. (2010) Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1690-703
Choi SS, Witek RP, Yang L, et al. (2010) Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells. Hepatology (Baltimore, Md.). 52: 278-90
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