Isabelle Deschenes
Affiliations: | Experimental Medicine | Universite Laval (Canada) |
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Children
Sign in to add traineeXi Du | research assistant | 2008-2010 | Case Western |
Yang Zheng | grad student | 2017-2022 | Case Western |
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Publications
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Chinthalapudi K, Biswas R, López-Serrano A, et al. (2024) Structural basis of human Na1.5 gating mechanisms. Research Square |
Deschênes I, Biswas R, Chinthalapudi K. (2024) Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment. Heart Rhythm. 21: 124-125 |
Loyo-Celis V, Patel D, Sanghvi S, et al. (2023) Biophysical Characterization of Chloride Intracellular Channel 6 (CLIC6). The Journal of Biological Chemistry. 105349 |
Zheng Y, Deschenes I. (2022) Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel Na1.5 to Anti-Arrhythmic Drugs. The Journal of Pharmacology and Experimental Therapeutics |
Clatot J, Coulombe A, Deschênes I, et al. (2022) Trafficking and Gating Cooperation Between Deficient Na1.5-mutant Channels to Rescue I. Frontiers in Bioscience (Landmark Edition). 27: 209 |
Zheng Y, Wan X, Yang D, et al. (2021) A Heart Failure-Associated Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel. Frontiers in Physiology. 12: 661429 |
Hu RM, Song EJ, Tester DJ, et al. (2021) Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R. Channels (Austin, Tex.). 15: 253-261 |
Poulin H, Mercier A, Djemai M, et al. (2021) iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities. Scientific Reports. 11: 2500 |
Zheng Y, Wan X, Yang D, et al. (2021) A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel Frontiers in Physiology. 12 |
Nowak MB, Greer-Short A, Wan X, et al. (2020) Intercellular Sodium Regulates Repolarization in Cardiac Tissue with Sodium Channel Gain of Function. Biophysical Journal |