Robert MacLaren
Affiliations: | University of Oxford, Oxford, United Kingdom |
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Parents
Sign in to add mentorJeremy S. H. Taylor | grad student | 1992-1995 | Oxford | |
(Doctor of Philosophy (DPhil)) |
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Publications
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MacLaren RE, Audo I, Fischer MD, et al. (2024) An Open-Label Phase II Study Assessing the Safety of Bilateral, Sequential Administration of Retinal Gene Therapy in Participants with Choroideremia: The GEMINI Study. Human Gene Therapy |
Yusuf IH, Burgoyne T, Salman A, et al. (2024) Rescue of cone and rod photoreceptor function in a CDHR1-model of age-related retinal degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy |
MacLaren RE, Lam BL, Fischer MD, et al. (2024) A Prospective, Observational, Non-Interventional Clinical Study of Participants With Choroideremia: The NIGHT Study. American Journal of Ophthalmology |
Yusuf IH, MacLaren RE. (2023) Choroideremia: Toward Regulatory Approval of Retinal Gene Therapy. Cold Spring Harbor Perspectives in Medicine |
Martinez-Fernandez de la Camara C, Cehajic-Kapetanovic J, MacLaren RE. (2023) Emerging gene therapy products for RPGR-associated X-linked retinitis pigmentosa. Expert Opinion On Emerging Drugs. 27: 431-443 |
Cehajic-Kapetanovic J, Martinez-Fernandez de la Camara C, Birtel J, et al. (2022) Impaired glutamylation of RPGR underlies the cone-dominated phenotype associated with truncating distal ORF15 variants. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208707119 |
Leroy BP, Fischer MD, Flannery JG, et al. (2022) Gene therapy for inherited retinal disease: long-term durability of effect. Ophthalmic Research |
Poli FE, Yusuf IH, Clouston P, et al. (2022) MERTK missense variants in three patients with retinitis pigmentosa. Ophthalmic Genetics. 1-9 |
McClements ME, Staurenghi F, Visel M, et al. (2022) AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration. Biomed Research International. 2021: 1-8 |
McClements ME, Steward H, Atkin W, et al. (2022) Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids. Translational Vision Science & Technology. 11: 3 |