Claire Le Pichon

Affiliations: 
Columbia University, New York, NY 
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"Claire Le Pichon"
Mean distance: 14.88 (cluster 11)
 
SNBCP

Parents

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Stuart Firestein grad student 2001-2007 Columbia
 (Neurobehavioral impairments of prion protein deficient mice in olfactory tasks: Towards a functional understanding of the cellular prion protein PrP(C).)

Children

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Mor R Alkaslasi grad student Brown/NIH
Zoe Piccus grad student Brown/NIH
Li Chen grad student 2017- NIH/Bethesda MD
Jorge Gomez-Deza post-doc 2017- NIH
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Publications

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Szczot M, Pogorzala LA, Solinski HJ, et al. (2017) Cell-Type-Specific Splicing of Piezo2 Regulates Mechanotransduction. Cell Reports. 21: 2760-2771
Yamazaki M, Le Pichon CE, Jackson AC, et al. (2015) Relative contribution of TARPs γ-2 and γ-7 to cerebellar excitatory synaptic transmission and motor behavior. Proceedings of the National Academy of Sciences of the United States of America. 112: E371-9
Patel S, Cohen F, Dean BJ, et al. (2015) Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models. Journal of Medicinal Chemistry. 58: 401-18
Le Pichon CE, Chesler AT. (2014) The functional and anatomical dissection of somatosensory subpopulations using mouse genetics. Frontiers in Neuroanatomy. 8: 21
Estrada AA, Chan BK, Baker-Glenn C, et al. (2014) Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 57: 921-36
Chan BK, Estrada AA, Chen H, et al. (2013) Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 4: 85-90
Le Pichon CE, Dominguez SL, Solanoy H, et al. (2013) EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS. Plos One. 8: e62342
Sheng Z, Zhang S, Bustos D, et al. (2012) Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations. Science Translational Medicine. 4: 164ra161
Estrada AA, Liu X, Baker-Glenn C, et al. (2012) Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 55: 9416-33
Kennedy HS, Puth F, Van Hoy M, et al. (2011) A method for removing the brain and spinal cord as one unit from adult mice and rats. Lab Animal. 40: 53-7
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