Tsuyoshi Uehara

Affiliations: 
Harvard Medical School, Boston, MA, United States 
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"Tsuyoshi Uehara"
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Han W, Ma X, Balibar CJ, et al. (2020) Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Journal of the American Chemical Society
Hamrick JC, Docquier JD, Uehara T, et al. (2019) VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- and metallo-β-lactamases, restores activity of cefepime in and . Antimicrobial Agents and Chemotherapy
Ma X, Prathapam R, Wartchow C, et al. (2019) Structural and biological basis of small molecule inhibition of Escherichia coli LpxD acyltransferase essential for lipopolysaccharide biosynthesis. Acs Infectious Diseases
Sawyer WS, Wang L, Uehara T, et al. (2019) Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry. Plos One. 14: e0211803
Buss JA, Baidin V, Welsh MA, et al. (2018) A pathway-directed screen for inhibitors of the bacterial cell elongation machinery. Antimicrobial Agents and Chemotherapy
Kreamer NNK, Chopra R, Caughlan RE, et al. (2018) Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase. Scientific Reports. 8: 14124
Dean CR, Barkan DT, Bermingham A, et al. (2018) The monobactam LYS228: mode of action and mechanisms decreasing susceptibility of and . Antimicrobial Agents and Chemotherapy
Nilsson I, Grove K, Dovala D, et al. (2017) Molecular characterization and verification of azido 3,8-dideoxy-D-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide. The Journal of Biological Chemistry
Meeske AJ, Riley EP, Robins WP, et al. (2016) SEDS proteins are a widespread family of bacterial cell wall polymerases. Nature
Markovski M, Bohrhunter JL, Lupoli TJ, et al. (2016) Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity. Proceedings of the National Academy of Sciences of the United States of America
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